CAS 23873-85-0

Proligestone

Description:

Proligestone is a synthetic steroid compound primarily used for its progestational properties. It is classified as a synthetic progestin, which means it mimics the action of the natural hormone progesterone in the body. Proligestone is often utilized in veterinary medicine, particularly for reproductive management in animals, as it can help regulate estrous cycles and support pregnancy. The compound exhibits anti-estrogenic effects and is known for its ability to inhibit ovulation. In terms of its chemical structure, Proligestone features a steroid backbone, which is characteristic of many hormones, and it possesses specific functional groups that contribute to its biological activity. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are essential for understanding its efficacy and safety profile. As with any synthetic hormone, careful consideration of dosage and potential side effects is crucial in its application. Overall, Proligestone serves as an important tool in reproductive health management in veterinary practices.

Formula: C₂₄H₃₄O₄

InChI: InChI=1S/C24H34O4/c1-5-20-27-23(15(2)25)12-13-24(28-20)19-7-6-16-14-17(26)8-10-21(16,3)18(19)9-11-22(23,24)4/h14,18-20H,5-13H2,1-4H3/t18-,19+,20?,21-,22+,23-,24+/m0/s1

InChI key: InChIKey=MQSDUYIXZDSLSZ-QSDCUGRSSA-N

SMILES: C[C@@]12[C@]3([C@]4([C@](CC1)([C@]5(C)C(CC4)=CC(=O)CC5)[H])[H])CC[C@@]2(C(C)=O)OC(CC)O3

Synonyms:

• (1R,4aR,4bR,10aR,10bS,12aS)-1-acetyl-3-ethyl-10a,12a-dimethyl-1,5,6,9,10,10a,10b,11,12,12a-decahydro-1,4a-ethanophenanthro[1,2-d][1,3]dioxin-8(4bH)-one
• 1,4a-Ethano-4aH-phenanthro[1,2-d][1,3]dioxin, pregn-4-ene-3,20-dione deriv.
• 14,17-Dihydroxypregn-4-ene-3,20-dione, cyclic acetal with propionaldehyde
• 14,17-[Propylidenebis(oxy)]pregn-4-ene-3,20-dione
• 14α,17α-Propylidenedioxypregn-4-ene-3,20-dione
• Pregn-4-ene-3,20-dione, 14,17-[propylidenebis(oxy)]-
• Pregn-4-ene-3,20-dione, 14,17-dihydroxy-, cyclic acetal with propionaldehyde
• Proligestona
• Proligestona [INN-Spanish]
• Proligestone [INN:BAN]
• Proligestonum
• Proligestonum [INN-Latin]

Proligestone

CAS: 23873-85-0

Formula: C₂₄H₃₄O₄

Molecular weight: 386.54

Ref: 4Z-P-221001

Proligestone

CAS: 23873-85-0

Applications Proligestone is a derivative of 17α-Hydroxy Progesterone (H952330), which is a metabolite of Progesterone (P755900), a steroid hormone produced by the corpus luteum. Proligestone maintains the ability to affect the hypothalmic-pituitary-adrenocortical axis and glucose homeostasis.
References Pfiffner, N., et al.: J. Biol. Chem., 132, 459 (1940); Florey, K., et al.: Anal. Profiles Drug Subs.,4, 209 (1975); Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003); Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003); Zeinalov, O. et al.: Pharm. Chem. J., 46, 203 (2012); Selman, P. et al.: J. Reprod. Fertil. Suppl. 52, 345 (1997);

Formula: C₂₄H₃₄O₄

Color and Shape: Neat

Molecular weight: 386.52

Ref: TR-P755960

Proligestone

CAS: 23873-85-0

Proligestone is a dietary supplement that may be used to promote fertility, weight loss, and the control of symptoms related to menopause. It contains the active ingredient progesterone, which is a hormone that is needed for ovulation, pregnancy, and breast-feeding. Proligestone has been shown to have a number of effects on the body. Proligestone can reduce insulin sensitivity and increase plasma glucose levels in diabetic animals. Proligestone also stimulates the release of growth factors from human platelets, which can promote wound healing. In addition, it may improve bone mineral density in postmenopausal women.

Formula: C₂₄H₃₄O₄

Purity: Min. 98 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 386.52 g/mol

Ref: 3D-FP30125