CymitQuimica logo

CAS 2390-54-7

:

Thioflavin

Description:
Thioflavin, specifically Thioflavin T, is a synthetic organic compound commonly used as a fluorescent dye in biochemistry and molecular biology. It is characterized by its ability to bind to amyloid fibrils, making it a valuable tool for studying protein aggregation and misfolding, particularly in neurodegenerative diseases such as Alzheimer's. Thioflavin T exhibits strong fluorescence when bound to amyloid structures, allowing for the visualization and quantification of these aggregates under appropriate excitation wavelengths. The compound has a relatively low molecular weight and features a thiazole ring, which contributes to its fluorescent properties. Thioflavin T is typically soluble in water and exhibits a distinct color change upon binding to amyloid fibrils, which is utilized in various assays and imaging techniques. Its utility in research is complemented by its relatively low toxicity, making it suitable for use in live-cell imaging studies. Overall, Thioflavin T serves as an essential tool in the investigation of amyloid-related pathologies and the development of potential therapeutic strategies.
Formula:C17H19N2S·Cl
InChI:InChI=1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChI key:InChIKey=JADVWWSKYZXRGX-UHFFFAOYSA-M
SMILES:C[N+]1=C(SC=2C1=CC=C(C)C2)C3=CC=C(N(C)C)C=C3.[Cl-]
Synonyms:
  • 2-(4-(Dimethylamino)phenyl)-3,6-dimethylbenzo[d]thiazol-3-ium chloride
  • 2-[4-(Dimethylamino)Phenyl]-3,6-Dimethyl-1,3-Benzothiazol-3-Ium Chloride
  • 2-[p-(Dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride
  • 3,6-Dimethyl-2-dimethylaminophenylbenzothiazolium chloride
  • Acronol Lake Yellow T
  • Acronol Lake Yellow TC
  • Acronol Yellow T
  • Acronol Yellow TC
  • Acronol Yellow TC 180
  • Basic Flavine 8G
  • See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.