CAS 2391-03-9

(+-)-brompheniramine maleate

Description:

(±)-Brompheniramine maleate is an antihistamine commonly used to alleviate allergy symptoms, such as runny nose, sneezing, and itching. It is a salt formed from brompheniramine, a first-generation antihistamine, and maleic acid. This compound exhibits anticholinergic properties, which can lead to side effects such as drowsiness, dry mouth, and blurred vision. As a racemic mixture, it contains both enantiomers, which can exhibit different pharmacological effects. The substance is typically administered orally and is often found in combination with other medications in over-the-counter cold and allergy formulations. Its mechanism of action involves blocking histamine H1 receptors, thereby reducing the physiological effects of histamine release during allergic reactions. In terms of physical properties, (±)-brompheniramine maleate is usually presented as a white to off-white crystalline powder, soluble in water and alcohol. Proper storage conditions are essential to maintain its stability and efficacy, and it should be kept in a cool, dry place away from light.

Formula: C₂₀H₂₃BrN₂O₄

InChI: InChI=1/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1

SMILES: [C@H](CCN(C)C)(C1=CC=C(Br)C=C1)C2=CC=CC=N2.C(=C\C(O)=O)\C(O)=O

Synonyms:

• (3S)-3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine (2Z)-but-2-enedioate
• (S)-3-(4-Bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate
• 1-(p-Bromophenyl)-1-(2-pyridyl)-3-dimethylamine propane maleate
• 2-Pyridinepropanamine, γ-(4-bromophenyl)-N,N-dimethyl-, (S)-, (Z)-2-butenedioate (1:1)
• 2-Pyridinepropanamine, γ-(4-bromophenyl)-N,N-dimethyl-, (γS)-, (2Z)-2-butenedioate (1:1)
• Dexbrompheniramine Maleate
• Dimegan
• Disomer
• Disomer maleate
• Drixoral
• Pyridine, 2-[p-bromo-α-[2-(dimethylamino)ethyl]benzyl]-, maleate (1:1), (S)-
• d-2-[p-Bromo-α-(2-dimethylaminoethyl)benzyl]pyridine maleate
• Dexbrompheniramine Maleate (1178002)
• (+)-2-(p-bromo-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate
• (γS)-γ-(4-broMophenyl)-N,N-diMethyl-2-pyridinepropanaMine (2Z)-2-Butenedioate
• (+)-BROMPHENIRAMINE MALEATE SALT
• Dexbrompheniramine maleate (usan)
• Dexbrompheniramine maleate Q: What is the storage condition of
• Dexbrompheniramine maleate Q: What are the applications of
• d-brompheniraminemaleate
• Brompheniramine d-
• Dexbrompheniraminum
• disomermaleate
• (S)-2-[p-BroMo-α-[2-(diMethylaMino)ethyl]benzyl]pyridine Maleate
• Disophrol
• (S)-2-[p-bromo-alpha-[2-(dimethylamino)ethyl]benzyl]pyridinium (Z)-maleate (1:1)
• Dexbrompheniramine maleateQ: What is
• Dexbrompheniramine Maleate (200 mg)
• D03704
• Disomer (tn)
• DexbroMpheniraMin
• DEXBROMPHENIRAMINE MALEATE SALT
• (S)-BroMpheniraMine Maleate
• Dexbrompheniramine maleate Q: What is the CAS Number of
• gamma-(4-bromophenyl)-n,n-dimethyl-2-pyridinepropanamin(s)-2-pyridinepropanamin(z)-2-buten

Dexbrompheniramine Maleate

CAS: 2391-03-9

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₁₆H₁₉BrN₂·C₄H₄O₄

Color and Shape: Powder

Molecular weight: 318.07316

Ref: 45-1178002

(S)-Brompheniramine Maleate

CAS: 2391-03-9

Formula: C₁₆H₁₉BrN₂·C₄H₄O₄

Molecular weight: 319.25 116.07

Ref: 4Z-B-160012

Dexbrompheniramine maleate

CAS: 2391-03-9

Dexbrompheniramine is an antihistamine used for hay fever and urticaria, blocking H1 receptors in the body.

Formula: C₂₀H₂₃BrN₂O₄

Color and Shape: Solid

Molecular weight: 435.318

Ref: TM-T31396

(S)-Brompheniramine maleate

CAS: 2391-03-9

Brompheniramine is a non-sedating antihistamine with a variety of uses. It has been shown to inhibit the release of histamine and other mediators from mast cells, thereby preventing allergic reactions, such as hay fever, asthma, and chronic urticaria. Brompheniramine is also used for its sedative properties in the treatment of insomnia. Brompheniramine is a versatile building block that can be used to create complex compounds for research purposes or as speciality chemicals for high-quality fine chemical production.

Formula: C₂₀H₂₃BrN₂O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 435.31 g/mol

Ref: 3D-FB19340

(S)-Brompheniramine Maleate

Controlled Product

CAS: 2391-03-9

Applications The S-enantimer of Brompheniramine maleate (B686355) as antihistaminic.
References Walle, T., et al.: Biochem. Pharmacol., 37, 115 (1988), Yang, W., et al.: J. Pharm. Pharmacol., 56, 703 (2004), Xu, H., et al.: Anal. Sci., 20, 1409 (2004),

Formula: C₂₀H₂₃BrN₂O₄

Color and Shape: Neat

Molecular weight: 435.31

Ref: TR-B686335