CAS 23918-98-1

Eritadenine

Description:

Eritadenine, with the CAS number 23918-98-1, is a purine derivative and a naturally occurring nucleoside analog. It is primarily known for its role in the metabolism of adenosine and is found in certain species of fungi, particularly in the mushroom species *Pleurotus ostreatus* (oyster mushroom). Eritadenine is characterized by its ability to inhibit the enzyme S-adenosylhomocysteine hydrolase, which plays a crucial role in the regulation of adenosine levels in the body. This inhibition can lead to a decrease in the levels of S-adenosylhomocysteine and subsequently affect various biochemical pathways, including those involved in methylation processes. Eritadenine has garnered interest for its potential health benefits, including its effects on cholesterol metabolism and cardiovascular health. Additionally, it exhibits antioxidant properties, contributing to its potential therapeutic applications. As a chemical compound, eritadenine is soluble in water and exhibits stability under physiological conditions, making it a subject of research in pharmacology and nutrition.

Formula: C₉H₁₁N₅O₄

InChI: InChI=1S/C9H11N5O4/c10-7-5-8(12-2-11-7)14(3-13-5)1-4(15)6(16)9(17)18/h2-4,6,15-16H,1H2,(H,17,18)(H2,10,11,12)/t4-,6-/m1/s1

InChI key: InChIKey=LIEMBEWXEZJEEZ-INEUFUBQSA-N

SMILES: C([C@H]([C@H](C(O)=O)O)O)N1C=2C(N=C1)=C(N)N=CN2

Synonyms:

• (αR,βR)-6-Amino-α,β-dihydroxy-9H-purine-9-butanoic acid
• 23918-98-1
• 4-(6-Amino-9H-purin-9-yl)-4-deoxy-<span class="text-smallcaps">D</span>-erythronic acid
• 4-(6-Aminopurin-9-yl)-4-deoxy-<span class="text-smallcaps">D</span>-erythronic acid
• 4-(9-Adenyl)-<span class="text-smallcaps">D</span>-erythro-2,3-dihydroxybutyric acid
• 9H-Purine-9-butanoic acid, 6-amino-α,β-dihydroxy-, (αR,βR)-
• 9H-Purine-9-butanoic acid, 6-amino-α,β-dihydroxy-, [R-(R*,R*)]-
• <span class="text-smallcaps">D</span>-Eritadenine
• Eritadenine
• Erythronic acid, 4-(6-amino-9H-purin-9-yl)-4-deoxy-, <span class="text-smallcaps">D</span>-
• Lentinacin
• Lentysine
• [R-(R*,R*)]-6-Amino-a,b-dihydroxy-9H-purine-9-butanoic Acid
• (2R,3R)-4-(6-Amino-9H-purin-9-yl)-2,3-dihydroxybutanoic acid

Eritadenine

Controlled Product

CAS: 23918-98-1

Applications Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.
References Fukada, S., et al.: J. Nut., 136, 2797 (2006), Vilar, S., et al.: J. Med. Chem., 49, 1118 (2006), Yamada, T., et al.: Biochem. Pharmacol., 73, 981 (2007), Enman, J., et al.; J. Agric. Food Chem., 56, 2609 (2008),

Formula: C₉H₁₁N₅O₄

Color and Shape: Off White Solid

Molecular weight: 253.21

Ref: TR-E600100

Eritadenine

CAS: 23918-98-1

Eritadenine is a glycoside that has been found in the edible roots of plants belonging to the family Euphorbiaceae. Eritadenine is an inhibitor of malonic acid, which is a precursor for fatty acid synthesis. It has also been shown to have biological properties, such as inhibiting fat cell growth and reducing cholesterol levels in rats. Eritadenine can be detected with an analytical method that uses high-performance liquid chromatography coupled with a photodiode array detector. This method separates and identifies eritadenine from other compounds using polymerase chain reaction amplification on camp levels and sodium salts. Eritadenine can also be found in samples of liver cells or ethanolamine.

Formula: C₉H₁₁N₅O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 253.21 g/mol

Ref: 3D-FE22787

Eritadenine

CAS: 23918-98-1

Formula: C₉H₁₁N₅O₄

Molecular weight: 253.22

Ref: ST-EA-CP-A88109

Eritadenine

CAS: 23918-98-1

Eritadenine (Lentinacin) is a mushroom-derived compound acting as an effector at the adenosine P site in fat cell membranes, lowering cholesterol.

Formula: C₉H₁₁N₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 253.22

Ref: TM-T25385