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CAS 2392-39-4

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Dexamethasone sodium phosphate

Description:
Dexamethasone sodium phosphate is a synthetic corticosteroid and a sodium salt of dexamethasone, primarily used for its anti-inflammatory and immunosuppressive properties. It is characterized by its high solubility in water, which facilitates its use in injectable formulations. The compound is often employed in the treatment of various conditions, including allergies, autoimmune disorders, and certain types of cancer. Dexamethasone sodium phosphate acts by inhibiting the release of inflammatory mediators and modulating immune responses. Its pharmacological effects are attributed to its ability to bind to glucocorticoid receptors, leading to alterations in gene expression. The substance is typically administered via intramuscular or intravenous routes, and its dosage may vary based on the specific condition being treated. Common side effects can include increased blood sugar levels, fluid retention, and potential suppression of the adrenal gland function with prolonged use. As with all corticosteroids, careful monitoring is essential to mitigate adverse effects and ensure therapeutic efficacy.
Formula:C22H30FO8P·2Na
InChI:InChI=1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/t12-,15+,16+,17+,19+,20+,21+,22+;;/m1../s1
InChI key:InChIKey=ODEOTKLZVXBMJD-FCJDYXGNSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](F)([C@]4(C)C(CC3)=CC(=O)C=C4)[C@@H](O)C1)[H])(C[C@@H](C)[C@@]2(C(COP(=O)(O)O)=O)O)[H].[Na]
Synonyms:
  • (9R,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
  • Ak-Dex
  • Baldex
  • Colvasone
  • Corson
  • Corson (pharmaceutical)
  • Dalalone
  • Decadron phosphate
  • Decdan
  • Desashock
  • See more synonyms
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