CAS 2393-58-0

α-Muricholic acid

Description:

α-Muricholic acid is a bile acid that is primarily found in rodents and is a derivative of cholic acid. It is characterized by its unique structure, which includes a hydroxyl group at the 3-position and a double bond between the 5 and 6 positions of the steroid nucleus. This compound plays a significant role in the digestion and absorption of dietary fats and fat-soluble vitamins. α-Muricholic acid is known for its ability to influence lipid metabolism and has been studied for its potential effects on metabolic disorders. It exhibits amphipathic properties, allowing it to interact with both hydrophilic and hydrophobic substances, which is crucial for its function in emulsifying fats in the intestine. Additionally, it has been shown to have various biological activities, including potential anti-inflammatory effects. The compound is of interest in research related to metabolism, obesity, and liver function, making it a valuable subject in the study of bile acids and their physiological roles.

Formula: C₂₄H₄₀O₅

InChI: InChI=1S/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13-,14-,15-,16+,17+,18+,20+,21+,22+,23-,24-/m1/s1

InChI key: InChIKey=DKPMWHFRUGMUKF-GDYCBZMLSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@]([C@@H](CCC(O)=O)C)(CC4)[H])[H])([C@H](O)[C@@H](O)[C@@]1(C[C@H](O)CC2)[H])[H])[H]

Synonyms:

• 5β-Cholanic acid, 3α,6β,7α-trihydroxy-
• 5β-Cholan-24-oic acid, 3α,6β,7α-trihydroxy-
• α-Muricholic acid
• (3α,5β,6β,7α)-3,6,7-Trihydroxycholan-24-oic acid
• Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6β,7α)-

(3a,5b,6b,7a)-3,6,7-trihydroxy-Cholan-24-oic acid

CAS: 2393-58-0

Formula: C₂₄H₄₀O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 408.5714

Ref: IN-DA00C2PU

α-Muricholic Acid

CAS: 2393-58-0

Formula: C₂₄H₄₀O₅

Molecular weight: 408.58

Ref: 4Z-C-5769

α-Muricholic acid

CAS: 2393-58-0

α-Muricholic acid is the most abundant primary bile acid in rodents.

Formula: C₂₄H₄₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 408.57

Ref: TM-T19623

alfa-Muricholic-d5 Acid

CAS: 2393-58-0

Formula: C₂₄H₃₅D₅O₅

Molecular weight: 413.61

Ref: 4Z-C-5770

α-Muricholic Acid

Controlled Product

CAS: 2393-58-0

Applications α-Muricholic Acid is an bile acid found in urine. Studies have linked α-Muricholic in the understanding of the complex signaling pathways of hepatic lipid abnormalities with type 2 diabetes and a treatment target for this condition.
References Haeusier, R.A., et al.: Cell. Metabolism., 15, 65 (2012); Chen, K.H., et al.: Am. J. Physiol., 301, E853 (2011);

Formula: C₂₄H₄₀O₅

Color and Shape: Neat

Molecular weight: 408.57

Ref: TR-M732750

α-Muricholic Acid-d5

Controlled Product

CAS: 2393-58-0

Formula: C₂₄D₅H₃₅O₅

Color and Shape: Neat

Molecular weight: 413.602

Ref: TR-M732752

5β-Cholanic acid-3α,6β,7α-triol

Controlled Product

CAS: 2393-58-0

a murine-specific primary bile acid.  It has been shown that plasma, liver, and muscle levels of α-muricholic acid are increased in mice switched from a high-fat to low-fat diet.

Formula: C₂₄H₄₀O₅

Purity: Min. 95%

Molecular weight: 408.57 g/mol

Ref: 3D-FC182960