CAS 23979-41-1

(R)-Naproxen

Description:

(R)-Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its chiral structure, with the (R)-enantiomer being the active form that exhibits greater potency compared to its (S)-counterpart. The compound is typically presented as a white to off-white crystalline powder and is soluble in organic solvents like ethanol and methanol, but has limited solubility in water. Its mechanism of action involves the inhibition of cyclooxygenase (COX) enzymes, leading to a decrease in the synthesis of prostaglandins, which are mediators of inflammation and pain. (R)-Naproxen is commonly used to treat conditions such as arthritis, menstrual pain, and other inflammatory disorders. It is important to note that, like other NSAIDs, it may have side effects, including gastrointestinal issues and cardiovascular risks, particularly with long-term use. The compound is often administered in various formulations, including tablets and extended-release forms, to provide sustained therapeutic effects.

Formula: C₁₄H₁₄O₃

InChI: InChI=1/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m1/s1

InChI key: InChIKey=CMWTZPSULFXXJA-SECBINFHSA-N

SMILES: [C@@H](C(O)=O)(C)C1=CC2=C(C=C(OC)C=C2)C=C1

Synonyms:

• (-)-(R)-2-(6-Methoxy-2-naphthyl)propionic acid
• (-)-2-(6-Methoxy-2-naphthyl)propionic acid
• (-)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
• (-)-Naproxen
• (2R)-2-(6-methoxynaphthalen-2-yl)propanoic acid
• (R)-2-(6-Methoxynaphthalen-2-yl)propanoic acid
• (R)-6-Methoxy-alpha-methylnaphthalene-1-acetic acid
• (αR)-6-Methoxy-α-methyl-2-naphthaleneacetic acid
• 2-(6-Methoxynaphthalen-1-Yl)Propanoic Acid
• 2-Naphthaleneacetic acid 6-methoxy-α-methyl-, (αR)-
• 2-Naphthaleneacetic acid, 6-methoxy-α-methyl-, (R)-
• l-Naproxen
• (R)-NAPROXEN
• (R)-(-)-6-Methoxy-alpha-Methyl-2-naphthaleneacetic acid 98%
• (R)-6-METHOXY-A-METHYL-2-NAPHTHALENEACETIC ACID
• (r)-(-)-6-methoxy-α-methyl-2-naphthaleneacetic acid
• Einecs 245-966-6
• Naproxen EP IMpurity G
• (2R)-2-(6-Methoxynaphth-2-yl)propanoic acid
• (R)-α-Methyl-6-methoxy-2-naphthaleneacetic acid
• (R)-α-Methyl-6-methoxynaphthalene-2-acetic acid
• (R)-(-)-6-METHOXY-ALPHA-METHYL-2-NAPHTH&
• 2-Naphthaleneacetic acid, 6-methoxy-a-methyl-, (R)- (8CI)
• (R)-Naproxen, (2R)-2-(6-Methoxynaphth-2-yl)propionic acid, 2-[(1R)-1-Carboxyethyl]-6-methoxynaphthalene
• (R)-(-)-6-METHOXY-ALPHA-METHYL-2-NAPHTHALENEACETIC ACID

Naproxen Related Compound G ((R)-2-(6-Methoxynaphthalen-2-yl)propanoic acid)

CAS: 23979-41-1

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc not elsewhere specified or included

Formula: C₁₄H₁₄O₃

Color and Shape: Powder

Molecular weight: 230.09429

Ref: 45-1457436

2-​Naphthaleneacetic acid, 6-​methoxy-​α-​methyl-​, (αR)​-

CAS: 23979-41-1

Formula: C₁₄H₁₄O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 230.2592

Ref: IN-DA003CBL

(R)-Naproxen

CAS: 23979-41-1

(R)-Naproxen: anti-inflammatory with antipyretic and analgesic effects; treats gout, dysmenorrhea, rheumatoid arthritis.

Formula: C₁₄H₁₄O₃

Purity: 99.62% - 99.94%

Color and Shape: Solid

Molecular weight: 230.26

Ref: TM-T0855

(R)-Naproxen

CAS: 23979-41-1

(R)-Naproxen

Purity: ≥98%

Molecular weight: 230.26g/mol

Ref: 54-BUP17820

Naproxen EP Impurity G (Naproxen USP Related Compound G, (R)-Naproxen)

CAS: 23979-41-1

Formula: C₁₄H₁₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 230.26

Ref: 4Z-N-2320

(2R)-2-(6-Methoxynaphthalen-2-yl)propanoic Acid ((R)-Naproxen)

Controlled Product

CAS: 23979-41-1

Formula: C₁₄H₁₄O₃

Color and Shape: White To Off-White

Molecular weight: 230.26

Ref: 86-MM0152.25

(2R)-2-(6-Methoxynaphth-2-yl)propanoic acid

CAS: 23979-41-1

(2R)-2-(6-Methoxynaphth-2-yl)propanoic acid

Formula: C₁₄H₁₄O₃

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 230.26g/mol

Ref: 54-OR16409

Naproxen EP Impurity G

CAS: 23979-41-1

Formula: C₁₄H₁₄O₃

Molecular weight: 230.26

Ref: ST-EA-CP-N2007

(R)-2-(6-Methoxynaphthalen-2-yl)propanoic acid

CAS: 23979-41-1

Formula: C₁₄H₁₄O₃

Purity: 98%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 230.263

Ref: 10-F211429

(R)-Naproxen

Controlled Product

CAS: 23979-41-1

Formula: C₁₄H₁₄O₃

Color and Shape: White To Off-White

Molecular weight: 230.26

Ref: TR-N377510

(R)-Naproxen

CAS: 23979-41-1

COX1/2 inhibitor; nonsteroidal anti-inflammatory drug

Formula: C₁₄H₁₄O₃

Purity: Min. 95%

Color and Shape: White to off-white solid.

Molecular weight: 230.26 g/mol

Ref: 3D-FN26156