CAS 23981-47-7

6-Methoxy-2-naphthylacetic acid

Description:

6-Methoxy-2-naphthylacetic acid, with the CAS number 23981-47-7, is an organic compound characterized by its naphthalene structure, which is a fused bicyclic aromatic hydrocarbon. This compound features a methoxy group (-OCH3) at the 6-position of the naphthalene ring and an acetic acid moiety attached to the 2-position. It is typically a white to off-white solid and is soluble in organic solvents, reflecting its hydrophobic nature due to the aromatic system. The presence of the methoxy group enhances its lipophilicity and may influence its biological activity. This compound is of interest in various fields, including medicinal chemistry and pharmacology, due to its potential therapeutic applications. Its structure allows for interactions with biological targets, making it a candidate for further research in drug development. As with many organic acids, it may exhibit acidic properties, and its behavior in solution can be influenced by pH and solvent polarity. Safety data should be consulted for handling and storage guidelines.

Formula: C₁₃H₁₂O₃

InChI: InChI=1S/C13H12O3/c1-16-12-5-4-10-6-9(7-13(14)15)2-3-11(10)8-12/h2-6,8H,7H2,1H3,(H,14,15)

InChI key: InChIKey=PHJFLPMVEFKEPL-UHFFFAOYSA-N

SMILES: C(C(O)=O)C1=CC2=C(C=C(OC)C=C2)C=C1

Synonyms:

• (6-Methoxynaphthalen-2-Yl)Acetic Acid
• 2-(2-Methoxynaphthalen-6-yl)acetic acid
• 2-(6-Methoxy-2-naphthyl)acetic acid
• 2-(6-Methoxynaphthalen-2-yl)acetic acid
• 2-(6-Methoxynaphthalen-2-yl)aceticacid
• 2-Naphthaleneacetic acid, 6-methoxy-
• 6-Methoxy-2-naphthaleneacetic acid
• 6-Methoxy-2-naphthylacetic acid
• 6-Metossi-2-naphtil acetico
• 6-Metossi-2-naphtil acetico [Italian]
• Brl 10720
• Brn 2371586
• 6-Methoxynaphthalene-2-acetic acid

6-Methoxy-2-Naphthylacetic Acid

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 216.2326

Ref: IN-DA00BDTH

α-Demethylnaproxen

CAS: 23981-47-7

α-Demethylnaproxen

Purity: ≥95%

Molecular weight: 216.23g/mol

Ref: 54-BUP11853

Naproxen EP Impurity I

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Color and Shape: Pale Yellow Solid

Molecular weight: 216.24

Ref: 4Z-N-234

6-Methoxy-2-naphthylacetic acid

CAS: 23981-47-7

6-Methoxy-2-naphthylacetic acid

Formula: C₁₃H₁₂O₃

Purity: 97%

Color and Shape: yellow solid

Molecular weight: 216.23g/mol

Ref: 54-OR315155

2-(6-Methoxynaphthalen-2-yl)acetic Acid

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Purity: >95.0%(GC)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 216.24

Ref: 3B-M3326

α-Demethylnaproxen

Controlled Product

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Color and Shape: Neat

Molecular weight: 216.23

Ref: 86-MM0152.01

α-Demethylnaproxen

CAS: 23981-47-7

α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)

Formula: C₁₃H₁₂O₃

Purity: 97.57%

Color and Shape: Off-White Solid

Molecular weight: 216.23

Ref: TM-T7662

Naproxen EP Impurity I

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Molecular weight: 216.24

Ref: ST-EA-CP-N2009

6-Methoxy-2-naphthaleneacetic Acid (Desmethyl Naproxen)

Controlled Product

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Color and Shape: White

Molecular weight: 216.23

Ref: TR-M264695

6-Methoxy-2-naphthaleneacetic acid

CAS: 23981-47-7

6-Methoxy-2-naphthaleneacetic acid (6-MNA) is a nonsteroidal anti-inflammatory drug that is used to treat patients with chronic pain. 6-MNA has been shown to be an effective treatment for osteoarthritis, rheumatoid arthritis and other inflammatory conditions. It inhibits the production of prostaglandins and leukotrienes by inhibiting the enzyme cyclooxygenase, which is responsible for the conversion of arachidonic acid to these mediators. 6-MNA can also inhibit the activity of α1-acid glycoprotein and increase the activity of human serum albumin, which may contribute to its antiinflammatory effect. 6-MNA has several side effects including nausea, vomiting, diarrhea and abdominal pain. These adverse reactions are caused by inhibition of protein synthesis in the stomach lining, which leads to decreased production of mucus and bicarbonate ions.

Formula: C₁₃H₁₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 216.23 g/mol

Ref: 3D-FM25226

2-(6-Methoxynaphthalen-2-yl)acetic acid

CAS: 23981-47-7

Formula: C₁₃H₁₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 216.236

Ref: 10-F091555