CAS 2410081-60-4

2-Propanol, 1-[[2-[2-[2-[4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenoxy]ethoxy]ethoxy]ethyl]amino]-3-[4-(phenylmethoxy)-3-(3-phenylpropoxy)phenoxy]-, (2R)-

Description:

2-Propanol, 1-[[2-[2-[2-[4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenoxy]ethoxy]ethoxy]ethyl]amino]-3-[4-(phenylmethoxy)-3-(3-phenylpropoxy)phenoxy]-, (2R)-, identified by CAS number 2410081-60-4, is a complex organic compound characterized by its multi-functional structure. It features a propanol backbone, which is a three-carbon alcohol, and is substituted with various aromatic and heterocyclic groups, including a pyrazolo-pyrimidine moiety and multiple ether linkages. This compound exhibits properties typical of both alcohols and amines, such as solubility in polar solvents and potential hydrogen bonding capabilities. The presence of trifluoromethyl groups suggests enhanced lipophilicity and potential biological activity. Its intricate structure may confer specific pharmacological properties, making it of interest in medicinal chemistry. The compound's synthesis and application would likely be relevant in drug development or as a biochemical probe, although detailed studies would be necessary to elucidate its full characteristics and potential uses.

Formula: C₅₁H₅₀F₆N₄O₇

Synonyms:

• 2-Propanol, 1-[[2-[2-[2-[4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]phenoxy]ethoxy]ethoxy]ethyl]amino]-3-[4-(phenylmethoxy)-3-(3-phenylpropoxy)phenoxy]-, (2R)-

PHTPP-1304

CAS: 2410081-60-4

PHTPP-1304, a chimeric autophagy-targeting compound (AUTOTAC) based on PHTPP, induces p62 self-oligomerization and degrades estrogen receptor ERβ (DC50: ~2 nM, HEK293T). Additionally, PHTPP-1304 facilitates the formation of p62+ERβ+ puncta in a dose-dependent manner, influencing autophagic flux.

Formula: C₅₁H₅₀F₆N₄O₇

Color and Shape: Solid

Molecular weight: 944.96

Ref: TM-T88793