CAS 2411100-70-2

Sting agonist 12b

Controlled Product

CAS: 2411100-70-2

Sting agonist 12b is a research tool for the study of G-protein coupled receptors. It is an activator ligand that binds to the receptor and causes a conformational change in the receptor protein, which activates or inhibits an ion channel. Sting agonist 12b has been shown to bind to α1A-adrenergic receptors and inhibit cAMP production, while also binding to β2-adrenergic receptors and activating cAMP production. This compound has been shown to bind to human IgE and induce histamine release from mast cells. Sting agonist 12b is highly purified (>90%) with a purity of >99% by HPLC and exhibits no detectable impurities by NMR spectroscopy.

Formula: C₁₆H₁₃NO₂

Purity: Min. 95%

Molecular weight: 251.28 g/mol

Ref: 3D-LWD10070

STING Agonist 12b

CAS: 2411100-70-2

STING agonist 12b activates human/mouse STING, binds with Kd 26.4 μM, prompts interferon, and induces TNF-a, IL-6, IP-10, IL-1b in THP-1 cells.

Formula: C₁₆H₁₅NO₂

Color and Shape: Solid

Molecular weight: 253.3

Ref: TM-T38159