CAS 24125-16-4

leupeptin hydrochloride from*microbial source

Description:

Leupeptin hydrochloride, with the CAS number 24125-16-4, is a potent protease inhibitor derived from microbial sources, specifically from the fermentation of certain actinomycetes. It is primarily used in biochemical research to inhibit serine and cysteine proteases, making it valuable in studies involving protein degradation and processing. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its use in various biological assays. Leupeptin is known for its ability to stabilize proteins during purification and analysis, thereby preserving their functional integrity. It is commonly utilized in cell culture and in the preparation of cell lysates to prevent proteolytic degradation. Additionally, leupeptin has been studied for its potential therapeutic applications, including its role in cancer research and neuroprotection. However, like many protease inhibitors, it should be handled with care, as it may have specific safety and toxicity considerations in laboratory settings.

Formula: C₂₀H₃₉ClN₆O₄

InChI: InChI=1/C20H38N6O4.ClH/c1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;/h11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);1H

SMILES: CC(C)CC(C(=NC(CC(C)C)C(=NC(CCCNC(=N)N)C=O)O)O)N=C(C)O.Cl

Leupeptin hydrochloride

CAS: 24125-16-4

Leupeptin hydrochloride

Formula: C₂₀H₃₈N₆O₄·ClH

Purity: >90%

Color and Shape: Solid

Molecular weight: 463.01g/mol

Ref: 54-BIMI2442

Leupeptin hydrochloride

CAS: 24125-16-4

Formula: C₂₀H₃₈N₆O₄·HCl

Purity: ≥ 90.0%

Color and Shape: White to off-white powder

Molecular weight: 463.01

Ref: 7W-GL6840

Leupeptin HCl

CAS: 24125-16-4

Leupeptin HCl is a drug that inhibits the activity of proteases. It has been shown to have anti-tuberculosis properties and has been used in combination with other drugs for this purpose. Leupeptin HCl binds to the catalytic site of the enzyme, which prevents access by substrates and competitive inhibitors, thus inhibiting its activity. The drug has also been shown to inhibit mitochondrial membrane potential in damaged cells; it blocks calcium ion influx through voltage-dependent channels in damaged cells and protects against cytosolic calcium overload. Leupeptin HCl has been shown to have locomotor stimulant effects on rats, as well as biological properties such as binding to monoclonal antibodies or eosinophil peroxidase.

Formula: C₂₀H₃₈N₆O₄·HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 463.01 g/mol

Ref: 3D-FL29628

LEUPEPTIN HYDROCHLORIDE

CAS: 24125-16-4

Formula: C₂₀H₃₉ClN₆O₄

Purity: 90%

Molecular weight: 463.0145

Ref: IN-DA00BG0T