CAS 2413-38-9

Flupentixol dihydrochloride

Description:

Flupentixol dihydrochloride is an antipsychotic medication primarily used in the treatment of schizophrenia and other mental health disorders. It belongs to the thioxanthene class of neuroleptics and functions as a dopamine receptor antagonist, particularly targeting D2 receptors in the brain. This compound is characterized by its ability to alleviate symptoms of psychosis, including hallucinations and delusions, while also exhibiting anxiolytic and antidepressant properties. Flupentixol dihydrochloride is typically administered in its dihydrochloride salt form, which enhances its solubility and bioavailability. The substance is often available in both oral and injectable formulations, allowing for flexibility in treatment regimens. Common side effects may include sedation, weight gain, and extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its pharmacological profile, careful monitoring is essential during treatment to manage potential adverse effects and ensure therapeutic efficacy. Overall, flupentixol dihydrochloride is a valuable option in the pharmacotherapy of various psychiatric conditions.

Formula: C₂₃H₂₅F₃N₂OS·2ClH

InChI: InChI=1S/C23H25F3N2OS.2ClH/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29;;/h1-2,4-8,16,29H,3,9-15H2;2*1H

InChI key: InChIKey=IOVDQEIIMOZNNA-UHFFFAOYSA-N

SMILES: C(CCN1CCN(CCO)CC1)=C2C=3C(SC=4C2=CC=CC4)=CC=C(C(F)(F)F)C3.Cl

Synonyms:

• (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazine-1-ethanol dihydrochloride
• 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, dihydrochloride
• 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride (1:2)
• 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]-, dihydrochloride
• 2-(4-{(3E)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol
• 2-(4-{(3Z)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride
• 2-(4-{3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride
• 4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazine-1-ethanol dihydrochloride
• Emergil
• Flupentixol Hydrochloride
• Flupentixol dihydrochloride
• Fx 703
• Metamin

Flupentixol Dihydrochloride

CAS: 2413-38-9

Color and Shape: Neat

Ref: 61-FOR0223.06

FLUPENTIXOL DIHYDROCHLORIDE CRS

CAS: 2413-38-9

FLUPENTIXOL DIHYDROCHLORIDE CRS

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Color and Shape: Powder

Molecular weight: 507.4395

Ref: 41-Y0000064

Flupentixol dihydrochloride

CAS: 2413-38-9

Flupentixol dihydrochloride

Formula: C₂₃H₂₅F₃N₂OS

Purity: 83.2%

Color and Shape: White. To. Light Brown

Molecular weight: 434.16397

Ref: 47-1132

(E/Z)-Flupentixol Dihydrochloride

CAS: 2413-38-9

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Purity: %

Color and Shape: Solid

Molecular weight: 507.4395

Ref: IN-DA006X7B

Flupentixol DiHCl (Mixture of Z and E Isomers)

CAS: 2413-38-9

Formula: C₂₃H₂₅F₃N₂OS·2HCl

Color and Shape: White To Off-White Solid

Molecular weight: 434.53 2*36.46

Ref: 4Z-F-572

Flupentixol dihydrochloride

CAS: 2413-38-9

Flupentixol dihydrochloride

Purity: ≥95%

Molecular weight: 507.43g/mol

Ref: 54-BUP10373

Flupentixol Dihydrochloride

CAS: 2413-38-9

Formula: C₂₃H₂₅F₃N₂OSClH

Color and Shape: White To Light Brown

Molecular weight: 507.44

Ref: 86-MM0223.06

Flupentixol dihydrochloride

CAS: 2413-38-9

Color and Shape: Neat

Ref: 04-CA13801580

Flupentixol dihydrochloride

CAS: 2413-38-9

Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Purity: 98.76% - >99.99%

Color and Shape: White Or Off-White Solid

Molecular weight: 507.43

Ref: TM-T5135

(E/Z)-Flupentixol-d4 Dihydrochloride

Controlled Product

CAS: 1246833-30-6, 2413-38-9

Stability Hygroscopic
Applications Neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),

Formula: C₂₃H₂₃D₄Cl₂F₃N₂OS

Color and Shape: Light Brown Solid

Molecular weight: 511.46

Ref: TR-F597982

4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride

Controlled Product

CAS: 2413-38-9

4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride is a potent antagonist of the 5-HT2A receptor. It has been shown to reduce body weight and food intake in animal models. The compound has also been shown to decrease motor activity and increase grooming behavior, which are symptoms of Parkinson's disease. 4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride is a Pgp substrate and can be used to measure the activity of this transporter in human serum, as well as determining its effect on renal function in rats.

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 507.44 g/mol

Ref: 3D-FT23498

(E/Z)-Flupentixol Dihydrochloride

Controlled Product

CAS: 2413-38-9

Applications Neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),

Formula: C₂₃H₂₅F₃N₂OS·2ClH

Color and Shape: White To Light Brown

Molecular weight: 507.44

Ref: TR-F598050