Afatinib Impurity N-Oxide, with the CAS number 2413212-11-8, is a chemical compound associated with the pharmaceutical agent Afatinib, which is used primarily in the treatment of certain types of cancer, particularly non-small cell lung cancer. As an impurity, it is a byproduct that may arise during the synthesis of Afatinib. The characteristics of this compound typically include its molecular structure, which features a nitrogen atom in an oxidized state, influencing its reactivity and stability. Impurities like N-Oxide can affect the pharmacological properties of the primary drug, including its efficacy and safety profile. The presence of such impurities is closely monitored in pharmaceutical manufacturing to ensure compliance with regulatory standards. Analytical techniques such as HPLC (High-Performance Liquid Chromatography) and mass spectrometry are often employed to identify and quantify impurities like Afatinib Impurity N-Oxide in drug formulations. Understanding the characteristics of this impurity is crucial for quality control and ensuring the therapeutic effectiveness of the final pharmaceutical product.

Afatinib Impurity N-Oxide

2413212-11-8: Afatinib Impurity N-Oxide, with the CAS number 2413212-11-8, is a chemical compound associated with the pharmaceutical agent Afatinib, which is used primarily in the treatment of certain types of cancer, particularly non-small cell lung cancer. As an impurity, it is a byproduct that may arise during the synthesis of Afatinib. The characteristics of this compound typically include its molecular structure, which features a nitrogen atom in an oxidized state, influencing its reactivity and stability. Impurities like N-Oxide can affect the pharmacological properties of the primary drug, including its efficacy and safety profile. The presence of such impurities is closely monitored in pharmaceutical manufacturing to ensure compliance with regulatory standards. Analytical techniques such as HPLC (High-Performance Liquid Chromatography) and mass spectrometry are often employed to identify and quantify impurities like Afatinib Impurity N-Oxide in drug formulations. Understanding the characteristics of this impurity is crucial for quality control and ensuring the therapeutic effectiveness of the final pharmaceutical product.

CAS 2413212-11-8

Afatinib Impurity N-Oxide

Afatinib N-Oxide

Ref: ST-EA-CP-A50018