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CAS 24166-13-0

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Cloxazolam

Description:
Cloxazolam is a benzodiazepine derivative primarily used for its anxiolytic and sedative properties. It is characterized by its ability to enhance the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased neuronal inhibition and a calming effect on the central nervous system. Cloxazolam typically appears as a white to off-white crystalline powder and is often administered in tablet form. Its pharmacological effects include anxiolysis, muscle relaxation, and anticonvulsant activity, making it useful in treating anxiety disorders and related conditions. The substance has a relatively long half-life, which contributes to its prolonged effects. However, like other benzodiazepines, it carries a risk of dependence, tolerance, and withdrawal symptoms with prolonged use. Cloxazolam is subject to regulatory controls in many countries due to its potential for abuse and the associated health risks. As with any medication, it is essential to use cloxazolam under medical supervision to mitigate risks and ensure appropriate therapeutic use.
Formula:C17H14Cl2N2O2
InChI:InChI=1S/C17H14Cl2N2O2/c18-11-5-6-15-13(9-11)17(12-3-1-2-4-14(12)19)21(7-8-23-17)10-16(22)20-15/h1-6,9H,7-8,10H2,(H,20,22)
InChI key:InChIKey=ZIXNZOBDFKSQTC-UHFFFAOYSA-N
SMILES:ClC1=C(C23C=4C(NC(=O)CN2CCO3)=CC=C(Cl)C4)C=CC=C1
Synonyms:
  • 10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
  • 10-Chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydrooxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
  • 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one
  • 10-chloro-11b-(2-chlorophenyl)-7,11b-dihydro-1H-[1,3]oxazolo[3,4-d][1,4]benzodiazepin-6(5H)-one
  • Betavel
  • Cloxazolazepam
  • Cs 370
  • Enadel
  • Lubalix
  • Mt 14-411
  • See more synonyms
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  • Cloxazolam
    TRC
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    Cloxazolam

    Controlled Product
    CAS:

    Applications Cloxazolam is a benzodiazepine derivative with anxiolytic, hypnotic and antihypertensive properties used as an anti-anxiety drug. It is metabolized into the active metabolite Delorezepam (D230675). Controlled Substance.
    References Oliveira-Silva, D. et al.: Biomed. Chrom., 23, 1266 (2009); Kamioka, T. et al.: Psychopharmacol., 52, 17 (1977); Fischer-Cornelssen, K.A. et al.: Arzneim.-Forsch., 31, 1757 (1981);

    Formula:C17H14Cl2N2O2
    Color and Shape:Neat
    Molecular weight:349.21

    Ref: TR-C587475

    5mg
    367.00€
    50mg
    2,301.00€