CAS 2417-73-4

methyl 2-bromomethyl benzoate

Description:

Methyl 2-bromomethyl benzoate is an organic compound characterized by its ester functional group and a bromomethyl substituent on the aromatic ring. It features a methyl ester derived from benzoic acid, where the benzoate moiety is attached to a bromomethyl group at the ortho position relative to the ester. This compound typically appears as a colorless to pale yellow liquid with a distinctive aromatic odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic aromatic structure. Methyl 2-bromomethyl benzoate can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions, making it a useful intermediate in organic synthesis. Its bromine atom can serve as a leaving group, facilitating the introduction of other functional groups. As with many brominated compounds, it is important to handle it with care due to potential toxicity and environmental concerns. Proper safety measures should be taken when working with this substance in a laboratory setting.

Formula: C₉H₉BrO₂

InChI: InChI=1/C9H9BrO2/c1-12-9(11)8-5-3-2-4-7(8)6-10/h2-5H,6H2,1H3

SMILES: COC(=O)c1ccccc1CBr

Synonyms:

• Methyl 2-bromomethylbenzoate
• 2-Bromomethyl-benzoic acid methyl ester

Methyl 2-bromomethylbenzoate

CAS: 2417-73-4

Formula: C₉H₉BrO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 229.0706

Ref: IN-DA007O45

Methyl 2-(bromomethyl)benzoate

CAS: 2417-73-4

Methyl 2-(bromomethyl)benzoate

Formula: C₉H₉BrO₂

Purity: 98%

Color and Shape: white solid

Molecular weight: 229.07056g/mol

Ref: 54-OR301372

Methyl 2-Bromomethylbenzoate

CAS: 2417-73-4

Applications Methyl 2-Bromomethylbenzoate is a reactant in the preparation of Methyl 2-((4-(2-(2-methylphenoxy)acetyl)piperazin-1-yl)methyl)benzoate with neuroprotective activity.
References Zhong, Y., et. al.: Chin. J. Struct. Chem., 33, 1096 (2014)

Formula: C₉H₉BrO₂

Color and Shape: Neat

Molecular weight: 229.070

Ref: TR-M295180

Methyl 2-(bromomethyl)benzoate

CAS: 2417-73-4

Methyl 2-(bromomethyl)benzoate (MBB) is a halogenated aromatic compound that inhibits the activity of DPP-4 and nitric oxide synthase. MBB has been shown to have anticancer potential by inhibiting translation and synthesis of proteins in cancer cells. It also inhibits the growth of MDA-MB-231 breast cancer cells, which is mediated by its interaction with mTORC1. MBB interacts with the sodium hydrogen exchanger in k562 cells, leading to an inhibitory effect on cellular respiration. This process is mediated by inhibition of DPP-4 activity, resulting in decreased levels of cyclic AMP and inhibition of protein synthesis.

Formula: C₉H₉BrO₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 229.1 g/mol

Ref: 3D-FM64249

Methyl (2-bromomethyl)benzoate

CAS: 2417-73-4

Formula: C₉H₉BrO₂

Purity: 95%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 229.073

Ref: 10-F046177