CAS 2417371-71-0

GNE-987

CAS: 2417371-71-0

GNE-987 is a potent chimeric BET degrader, binding BRD4 BD1/BD2 at IC50: 4.7/4.4 nM & has a DC50: 0.03 nM in EOL-1 AML cells.

Formula: C₅₆H₆₇F₂N₉O₈S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 1096.31

Ref: TM-T11441

7-(3,5-Difluoropyridin-2-yl)-N-(11-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecyl)-2-methyl-10-((methylsulfo

CAS: 2417371-71-0

7-(3,5-Difluoropyridin-2-yl)-N-(11-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecyl)-2-methyl-10-((methylsulfo

Purity: 95%

Molecular weight: 1096.34g/mol

Ref: 54-PC1007592

GNE-987

CAS: 2417371-71-0

GNE-987 is a potent anticancer drug that has been developed for the treatment of various types of tumors. It is an analog of kinase inhibitors and works by inhibiting specific kinases that are involved in cancer cell growth and survival. GNE-987 induces apoptosis (programmed cell death) in cancer cells, thereby preventing their proliferation. This drug has been shown to be effective against different types of human cancer cell lines, including Chinese hamster ovary cells. GNE-987 has also demonstrated activity against urinary tract tumors in preclinical studies. As a promising medicinal compound, GNE-987 holds great potential for the development of new cancer therapies.

Formula: C₅₆H₆₇F₂N₉O₈S₂

Purity: Min. 95%

Molecular weight: 1,096.3 g/mol

Ref: 3D-SWD37171