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CAS 2419-38-7

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N-Phthaloyl-L-leucine

Description:
N-Phthaloyl-L-leucine is an organic compound characterized by its structure, which includes a phthaloyl group attached to the amino acid leucine. This compound is typically used in peptide synthesis and as an intermediate in organic synthesis due to its ability to form stable derivatives. It is a white to off-white crystalline solid that is soluble in organic solvents but has limited solubility in water. The presence of the phthaloyl group enhances the compound's stability and reactivity, making it useful in various chemical reactions. N-Phthaloyl-L-leucine can participate in coupling reactions and is often employed in the synthesis of more complex molecules, including pharmaceuticals. Its properties, such as melting point and specific reactivity, can vary based on the purity and specific conditions under which it is handled. As with many chemical substances, proper safety precautions should be taken when handling N-Phthaloyl-L-leucine, including the use of personal protective equipment and adherence to safety data sheet guidelines.
Formula:C14H15NO4
InChI:InChI=1/C14H15NO4/c1-8(2)7-11(14(18)19)15-12(16)9-5-3-4-6-10(9)13(15)17/h3-6,8,11H,7H2,1-2H3,(H,18,19)/p-1/t11-/m1/s1
InChI key:InChIKey=RMOSZIHTPMEZAP-NSHDSACASA-N
SMILES:[C@H](CC(C)C)(C(O)=O)N1C(=O)C=2C(C1=O)=CC=CC2
Synonyms:
  • (2R)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanoate
  • (2S)-2-(1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl)-4-methylpentanoic acid
  • (2S)-2-(1,3-Dioxoisoindolin-2-yl)-4-methyl-pentanoic acid
  • (2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanoate
  • (2S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanoic acid
  • (αS)-1,3-Dihydro-α-(2-methylpropyl)-1,3-dioxo-2H-isoindole-2-acetic acid
  • 2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanoic acid
  • 2-Isoindolineacetic acid, α-isobutyl-1,3-dioxo-, <span class="text-smallcaps">L</span>-
  • 2H-Isoindole-2-acetic acid 1,3-dihydro-α-(2-methylpropyl)-1,3-dioxo-, (αS)-
  • 2H-Isoindole-2-acetic acid, 1,3-dihydro-α-(2-methylpropyl)-1,3-dioxo-, (S)-
  • See more synonyms
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