CAS 242138-07-4

Immunoglobulin G1,anti-(human immunoglobulin E Fc region) (human-mouse monoclonal E25 clonepSVIE25 g-chain), disulfide withhuman-mouse monoclonal E25 clone pSVIE25 k-chain, dimer (9CI)

Description:

Immunoglobulin G1 (IgG1), specifically the anti-human immunoglobulin E (IgE) Fc region derived from the human-mouse monoclonal E25 clone, is a recombinant antibody characterized by its specificity for the Fc portion of human IgE. This dimeric form consists of two heavy chains (g-chains) and two light chains (k-chains) linked by disulfide bonds, which contribute to its structural stability and functional efficacy. IgG1 is known for its ability to mediate immune responses, including opsonization and complement activation. The E25 clone is particularly significant in research and therapeutic contexts, as it can be utilized to study allergic responses and IgE-mediated diseases. The antibody's specificity allows it to bind selectively to human IgE, making it a valuable tool in both diagnostic and therapeutic applications. Its dimeric nature enhances its binding affinity and functional capabilities, making it an important component in immunological studies and potential treatments for allergic conditions.

Synonyms:

• Olizumab
• Omalizumab
• Xolair
• rhuMab-E 25

Omalizumab

CAS: 242138-07-4

Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)

Purity: 96.6% (SDS-PAGE); 98.2% (SEC-HPLC) - 99.60%

Color and Shape: Liquid

Molecular weight: 146.52 kDa

Ref: TM-T9926

Omalizumab, buffer solution

CAS: 242138-07-4

Monoclonal antibody against immunoglobulin E (IgE)

Purity: Min. 95 Area-%

Color and Shape: Powder

Ref: 3D-FO139134