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CAS 24219-97-4

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Mianserin

Description:
Mianserin is a tetracyclic antidepressant primarily used in the treatment of major depressive disorder. It is characterized by its unique chemical structure, which includes a dibenzocycloheptene core. Mianserin functions as a noradrenergic and specific serotonergic antidepressant (NaSSA), exerting its effects by antagonizing certain serotonin receptors (5-HT2 and 5-HT3) and enhancing norepinephrine release. This dual action contributes to its antidepressant properties while minimizing some of the side effects commonly associated with traditional selective serotonin reuptake inhibitors (SSRIs). Mianserin is known for its sedative effects, making it beneficial for patients with insomnia related to depression. It is typically administered orally and has a relatively long half-life, allowing for once-daily dosing. Common side effects may include sedation, weight gain, and dry mouth. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring during treatment.
Formula:C18H20N2
InChI:InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3
InChI key:InChIKey=UEQUQVLFIPOEMF-UHFFFAOYSA-N
SMILES:CN1CC2N(C=3C(CC=4C2=CC=CC4)=CC=CC3)CC1
Synonyms:
  • (.+-.)-Mianserin
  • 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine
  • 2-Methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine
  • Mianserina
  • Mianserine
  • Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
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Found 5 products.