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CAS 242478-37-1

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Solifenacin

Description:
Solifenacin is a synthetic antimuscarinic agent primarily used in the treatment of overactive bladder and associated symptoms such as urinary incontinence. It functions by selectively inhibiting the M3 muscarinic receptors in the bladder, leading to decreased bladder contractions and increased bladder capacity. Solifenacin is characterized by its chemical formula, which includes a specific arrangement of carbon, hydrogen, nitrogen, and oxygen atoms. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include dry mouth, constipation, and blurred vision, which are typical of anticholinergic medications. Solifenacin is metabolized in the liver, primarily by cytochrome P450 enzymes, and its pharmacokinetics can be influenced by factors such as age and liver function. Overall, Solifenacin represents a significant advancement in the management of urinary disorders, providing symptomatic relief for patients with overactive bladder.
Formula:C23H26N2O2
InChI:InChI=1S/C23H26N2O2/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19/h1-9,18,21-22H,10-16H2/t21-,22-/m0/s1
InChI key:InChIKey=FBOUYBDGKBSUES-VXKWHMMOSA-N
SMILES:C(O[C@@H]1C2CCN(C1)CC2)(=O)N3[C@H](C=4C(CC3)=CC=CC4)C5=CC=CC=C5
Synonyms:
  • (+)-Solifenacin
  • 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-
  • YM 905
  • Solifenacin
  • (R)-Quinuclidin-3-yl) (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
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Found 6 products.