CAS 242478-37-1

Solifenacin

Description:

Solifenacin is a synthetic antimuscarinic agent primarily used in the treatment of overactive bladder and associated symptoms such as urinary incontinence. It functions by selectively inhibiting the M3 muscarinic receptors in the bladder, leading to decreased bladder contractions and increased bladder capacity. Solifenacin is characterized by its chemical formula, which includes a specific arrangement of carbon, hydrogen, nitrogen, and oxygen atoms. The substance is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include dry mouth, constipation, and blurred vision, which are typical of anticholinergic medications. Solifenacin is metabolized in the liver, primarily by cytochrome P450 enzymes, and its pharmacokinetics can be influenced by factors such as age and liver function. Overall, Solifenacin represents a significant advancement in the management of urinary disorders, providing symptomatic relief for patients with overactive bladder.

Formula: C₂₃H₂₆N₂O₂

InChI: InChI=1S/C23H26N2O2/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19/h1-9,18,21-22H,10-16H2/t21-,22-/m0/s1

InChI key: InChIKey=FBOUYBDGKBSUES-VXKWHMMOSA-N

SMILES: C(O[C@@H]1C2CCN(C1)CC2)(=O)N3[C@H](C=4C(CC3)=CC=CC4)C5=CC=CC=C5

Synonyms:

• (+)-Solifenacin
• 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-
• YM 905
• Solifenacin
• (R)-Quinuclidin-3-yl) (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Solifenacin Succinate

CAS: 242478-37-1, 242478-38-2

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 480.56

Ref: 3B-S0944

2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-,(3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-

CAS: 242478-37-1

Formula: C₂₃H₂₆N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 362.4647

Ref: IN-DA019FSR

Solifenacin

CAS: 242478-37-1

Solifenacin

Purity: 98%

Molecular weight: 362.47g/mol

Ref: 54-OR1029754

Solifenacin

CAS: 242478-37-1

Solifenacin

Purity: ≥98%

Molecular weight: 362.46g/mol

Ref: 54-BUP14108

Solifenacin

CAS: 242478-37-1

Formula: C₂₃H₂₆N₂O₂

Molecular weight: 362.48

Ref: 4Z-S-181

Solifenacin

CAS: 242478-37-1

Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0,

Formula: C₂₃H₂₆N₂O₂

Purity: 99.87%

Color and Shape: Solid

Molecular weight: 362.46

Ref: TM-T8147