CAS 242478-38-2

Solifenacin succinate

Description:

Solifenacin succinate is a pharmaceutical compound primarily used as an antimuscarinic agent for the treatment of overactive bladder. It functions by selectively inhibiting the M3 muscarinic receptors in the bladder, leading to reduced detrusor muscle contractions and increased bladder capacity. This compound is characterized by its high selectivity for the M3 receptor, which minimizes side effects commonly associated with anticholinergic medications. Solifenacin succinate is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and a relatively long half-life, allowing for once-daily dosing. The substance is a white to off-white crystalline powder, soluble in water and various organic solvents. Its chemical structure includes a succinate moiety, which contributes to its pharmacological properties. As with many medications, potential side effects may include dry mouth, constipation, and urinary retention, necessitating careful patient monitoring. Overall, Solifenacin succinate represents an important therapeutic option for managing symptoms of overactive bladder.

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

InChI: InChI=1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21-,22-;/m0./s1

InChI key: InChIKey=RXZMMZZRUPYENV-VROPFNGYSA-N

SMILES: C(O[C@@H]1C2CCN(C1)CC2)(=O)N3[C@H](C=4C(CC3)=CC=CC4)C5=CC=CC=C5.C(CC(O)=O)C(O)=O

Synonyms:

• (3R)-1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate (1:1)
• 1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid
• 1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
• 1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate (1:1)
• 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-, butanedioate (1:1)
• Butanedioic acid, compd. with (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
• Vesicare
• Vesikur
• Ym 67905
• Solifenacin succinate

Solifenacin Succinate

CAS: 242478-37-1, 242478-38-2

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 480.56

Ref: 3B-S0944

Solifenacin succinate impurity standard

CAS: 118864-75-8, 1956436-64-8, 242478-38-2

Solifenacin succinate impurity standard

Color and Shape: White

Ref: 47-1282

SOLIFENACIN FOR SYSTEM SUITABILITY CRS

CAS: 242478-38-2

SOLIFENACIN FOR SYSTEM SUITABILITY CRS

Formula: C₂₇H₃₂N₂O₆

Color and Shape: Powder

Molecular weight: 480.5528

Ref: 41-Y0001743

SOLIFENACIN SUCCINATE CRS

CAS: 242478-38-2

SOLIFENACIN SUCCINATE CRS

Formula: C₂₇H₃₂N₂O₆

Color and Shape: Powder

Molecular weight: 480.5528

Ref: 41-Y0001763

Solifenacin succinate

CAS: 242478-38-2

Solifenacin succinate

Formula: C₂₇H₃₂N₂O₆

Purity: 99.8%

Color and Shape: White

Molecular weight: 480.22604

Ref: 47-1281

Solifenacin Succinate

CAS: 242478-38-2

Compounds containing a quinoline or isoquinoline ring-system, whether or not hydrogenated, not further fused, excluding drugs and pesticides

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Color and Shape: White Off-White Powder

Molecular weight: 480.22604

Ref: 45-1615300

1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid

CAS: 242478-38-2

Formula: C₂₇H₃₂N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 480.5528

Ref: IN-DA00393T

Solifenacin succinate

CAS: 242478-38-2

Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 muscarinic antagonist, which is used as a urologic agent.

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Purity: 99.85% - 99.98%

Color and Shape: Solid

Molecular weight: 480.56

Ref: TM-T0111

Solifenacin Succinate

CAS: 242478-38-2

Solifenacin Succinate

Purity: 98%

Molecular weight: 480.56g/mol

Ref: 54-OR1025050

Solifenacin Succinate

CAS: 242478-38-2

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Color and Shape: White To Off-White Solid

Molecular weight: 362.47 118.09

Ref: 4Z-S-185

Solifenacin succinate

CAS: 242478-38-2

Solifenacin succinate

Purity: ≥98%

Molecular weight: 480.56g/mol

Ref: 54-BUP14831

Solifenacin succinate

CAS: 242478-38-2

Formula: C₂₇H₃₂N₂O₆

Molecular weight: 480.55

Ref: 7W-GP2222

Solifenacin Succinate

CAS: 242478-38-2

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Color and Shape: Neat

Molecular weight: 480.55

Ref: 86-MM1342.00

Solifenacin-d5-N-Glucuronide

CAS: 242478-38-2

Formula: C₂₉H₂₉D₅N₂O₈

Molecular weight: 543.63

Ref: 4Z-S-1856

Solifenacin Succinate

Controlled Product

CAS: 242478-38-2

Stability Hygroscopic
Applications Muscarinic M3 receptor antagoinst. Used in treatment of urinary incontinence.
References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Color and Shape: White

Molecular weight: 480.55

Ref: TR-S676701

Solifenacin succinate

CAS: 242478-38-2

Muscarinic receptor antagonist

Formula: C₂₃H₂₆N₂O₂•C₄H₆O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 480.55 g/mol

Ref: 3D-FS14815

Solifenacin succinate - Bio-X ™

CAS: 242478-38-2

Solifenacin is a muscarinic antagonist drug that is used to treat symptoms associated with an overactive bladder such as urine urgency and urinary incontinence. This drug has high affinity for M1, M2 and M3 receptors, with its highest being for M3 receptors. Antagonism of these receptors prevent contraction of smooth muscles in the bladder.

Formula: C₂₃H₂₆N₂O₂·C₄H₆O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 480.55 g/mol

Ref: 3D-BS164410