CAS 242478-38-2: Solifenacin succinate
Description:Solifenacin succinate is a pharmaceutical compound primarily used as an antimuscarinic agent for the treatment of overactive bladder. It functions by selectively inhibiting the M3 muscarinic receptors in the bladder, leading to reduced detrusor muscle contractions and increased bladder capacity. This compound is characterized by its high selectivity for the M3 receptor, which minimizes side effects commonly associated with anticholinergic medications. Solifenacin succinate is typically administered orally and is known for its favorable pharmacokinetic profile, including good absorption and a relatively long half-life, allowing for once-daily dosing. The substance is a white to off-white crystalline powder, soluble in water and various organic solvents. Its chemical structure includes a succinate moiety, which contributes to its pharmacological properties. As with many medications, potential side effects may include dry mouth, constipation, and urinary retention, necessitating careful patient monitoring. Overall, Solifenacin succinate represents an important therapeutic option for managing symptoms of overactive bladder.
Formula:C23H26N2O2·C4H6O4
InChI:InChI=1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21-,22-;/m0./s1
InChI key:InChIKey=RXZMMZZRUPYENV-VROPFNGYSA-N
SMILES:O=C(O)CCC(=O)O.O=C(OC1CN2CCC1CC2)N3CCC=4C=CC=CC4C3C=5C=CC=CC5
- Synonyms:
- (3R)-1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate (1:1)
- 1-Azabicyclo[2.2.2]octan-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate butanedioic acid
- 1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
- 1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate butanedioate (1:1)
- 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo[2.2.2]oct-3-yl ester, (1S)-, butanedioate (1:1)
- Butanedioic acid, compd. with (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
- Vesicare
- Vesikur
- Ym 67905
- Solifenacin succinate
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