CAS 24277-39-2

N-(tert-Butoxycarbonyl)-L-glutamic acid 1-tert-butyl ester

Description:

N-(tert-Butoxycarbonyl)-L-glutamic acid 1-tert-butyl ester, with the CAS number 24277-39-2, is a chemical compound that belongs to the class of amino acid derivatives. It features a tert-butoxycarbonyl (Boc) protecting group, which is commonly used in peptide synthesis to protect the amino group of the amino acid. The presence of the L-glutamic acid moiety indicates that it is an L-enantiomer, which is significant in biological systems. The compound also contains a tert-butyl ester, which enhances its lipophilicity and stability. Typically, such compounds are utilized in organic synthesis, particularly in the preparation of peptides and other bioactive molecules. The characteristics of this substance include its solubility in organic solvents, stability under standard laboratory conditions, and potential reactivity in coupling reactions. Its structural features make it a valuable intermediate in the synthesis of more complex organic compounds, especially in pharmaceutical chemistry. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₁₄H₂₅NO₆

InChI: InChI=1S/C14H25NO6/c1-13(2,3)20-11(18)9(7-8-10(16)17)15-12(19)21-14(4,5)6/h9H,7-8H2,1-6H3,(H,15,19)(H,16,17)/t9-/m0/s1

InChI key: InChIKey=YMOYURYWGUWMFM-VIFPVBQESA-N

SMILES: [C@@H](NC(OC(C)(C)C)=O)(C(OC(C)(C)C)=O)CCC(O)=O

Synonyms:

• (4S)-5-(tert-Butoxy)-4-[[(tert-butoxy)carbonyl]amino]-5-oxopentanoic acid
• (4S)-5-[(2-Methylpropan-2-yl)oxy]-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoic acid
• (4S)-5-tert-Butoxy-4-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid
• (4S)-5-tert-butoxy-4-[(tert-butoxycarbonyl)amino]-5-oxopentanoic acid (non-preferred name)
• (S)-2-[(tert-Butoxycarbonyl)amino]pentanedioic acid 1-tert-butyl ester
• (S)-5-tert-Butoxy-4-(tert-butoxycarbonylamino)-5-oxopentanoic acid
• 5-Tert-Butoxy-4-[(Tert-Butoxycarbonyl)Amino]-5-Oxopentanoic Acid (Non-Preferred Name)
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester
• BOC-<span class="text-smallcaps">L</span>-glutamic acid tert-butyl ester
• Boc-<span class="text-smallcaps">L</span>-glutamic acid 1-tert-butyl ester
• Boc-Glu-OBut
• Boc-Glu-OtBu
• Boc-L-glutamic acid 1-tert-butyl ester
• Boc-L-glutamic acid α-tert.butyl ester
• Glutamic acid, N-carboxy-, N,1-di-tert-butyl ester, <span class="text-smallcaps">L</span>-
• N-(tert-Butoxycarbonyl)-<span class="text-smallcaps">L</span>-glutamic acid 1-tert-butyl ester
• N-Boc-glutamic acid tert-butyl ester
• N-a-BOC-L-Glu-O-tert-Bu
• N-tert-Butoxycarbonylglutamic acid α-tert-butyl ester
• N-α-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-glutamic acid α-tert butyl ester
• NSC 164659
• L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(1,1-dimethylethyl) ester
• N-(tert-Butoxycarbonyl)-L-glutamic acid 1-tert-butyl ester

1-tert-Butyl N-(tert-Butoxycarbonyl)-L-glutamate

CAS: 24277-39-2

Formula: C₁₄H₂₅NO₆

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystaline

Molecular weight: 303.36

Ref: 3B-B4534

N-Boc-L-glutamic acid 1-tert-butyl ester, 99%

CAS: 24277-39-2

Boc-Glu-OtBu is an N-terminal protected amino acid used in solid-phase peptide synthesis (SPPS) to make unique peptides containing glutamate tert-butyl ester residues. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label

Formula: C₁₄H₂₅NO₆

Purity: 99%

Molecular weight: 303.36

Ref: 02-H59842

Boc-Glu-OtBu

CAS: 24277-39-2

Educt for obtaining a protected derivative of Glu γ-aldehyde used in the Fischer indole synthesis of Ar-substituted tryptophans.

Formula: C₁₄H₂₅NO₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 303.36

Ref: 01-4000173

Boc-L-glutamic acid 1-tert-butyl ester

CAS: 24277-39-2

Formula: C₁₄H₂₅NO₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 303.3514

Ref: IN-DA0035YG

Boc-Glu-OtBu

CAS: 24277-39-2

Formula: C₁₄H₂₅NO₆

Molecular weight: 303.36

Ref: 7W-GM7058

Boc-Glu-OtBu

CAS: 24277-39-2

Boc-Glu-OtBu

Purity: 98%

Molecular weight: 303.36g/mol

Ref: 54-BI9884

Boc-Glu-OtBu

CAS: 24277-39-2

M06178 - Boc-Glu-OtBu

Formula: C₁₄H₂₅NO₆

Purity: 95%

Color and Shape: Solid, White powder

Molecular weight: 303.355

Ref: 10-M06178

Boc-L-glutamic acid a-t-butyl ester

CAS: 24277-39-2

Boc-L-glutamic acid a-t-butyl ester is a specific antibody that has been shown to be effective in the diagnosis of cancer. This antibody binds to an antigen expressed by liver cells and can be used as a marker for cancer. It has also been shown to have an adjuvant effect on vaccines, which may lead to better protection against disease. Boc-L-glutamic acid a-t-butyl ester can also be used in the treatment of pancreatitis and other acute ischemic conditions because it promotes the release of hydrogen chloride, which helps to relieve pain.

Formula: C₁₄H₂₅NO₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 303.35 g/mol

Ref: 3D-FB41683

N-Boc-glutamic Acid Tert-butyl Ester

Controlled Product

CAS: 24277-39-2

Formula: C₁₄H₂₅NO₆

Color and Shape: Neat

Molecular weight: 303.35

Ref: TR-B656135