CAS 24280-93-1

Mycophenolic acid

Description:

Mycophenolic acid is an organic compound with the chemical formula C17H20O6 and is classified as a selective immunosuppressant. It is primarily derived from the fungus Penicillium and is known for its role in inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH), which is crucial in the de novo synthesis pathway of purine nucleotides. This mechanism makes it particularly effective in preventing organ transplant rejection and treating autoimmune diseases. Mycophenolic acid appears as a white to off-white crystalline powder and is soluble in organic solvents like ethanol and dimethyl sulfoxide, but has limited solubility in water. Its pharmacological properties include anti-inflammatory effects, and it is often used in combination with other immunosuppressants to enhance efficacy and reduce the risk of rejection in transplant patients. However, it can also lead to side effects such as gastrointestinal disturbances and an increased risk of infections due to its immunosuppressive action. Proper monitoring and dosage adjustments are essential during its therapeutic use.

Formula: C₁₇H₂₀O₆

InChI: InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+

InChI key: InChIKey=HPNSFSBZBAHARI-RUDMXATFSA-N

SMILES: CC1=C2C(=C(O)C(C/C=C(/CCC(O)=O)\C)=C1OC)C(=O)OC2

Synonyms:

• (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid
• (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate
• (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
• (E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-
• 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (E)-
• 4-Hexenoic acid, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-, (E)-
• 6-(4-Hydroxy-6-Methoxy-7-Methyl-3-Oxo-1,3-Dihydro-2-Benzofuran-5-Yl)-4-Methylhex-4-Enoic Acid
• Acide Mycophenolique
• Acido Micofenolico
• Lilly 68618
• MPA
• Melbex
• Mycophenolic Acid From Penicillium Brevi-Compactum
• Mycophenolic Acid From Penicillium*Brevi-Compactu
• Mycophenolinsaure
• Nsc 129185

Mycophenolic Acid

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 320.34

Ref: 3B-M2216

Mycophenolic acid, 98%

CAS: 24280-93-1

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly

Formula: C₁₇H₂₀O₆

Purity: 98%

Molecular weight: 320.34

Ref: 02-J61905

Mycophenolic Acid

CAS: 24280-93-1

Color and Shape: Neat

Ref: 61-FOR1001.06

4-Hexenoic acid,6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, (4E)-

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 320.3371

Ref: IN-DA00I4O6

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

Formula: C₁₇H₂₀O₆

Purity: 98.79% - 99.77%

Color and Shape: Solid

Molecular weight: 320.34

Ref: TM-T1335

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid

Purity: ≥98%

Molecular weight: 320.34g/mol

Ref: 54-BUP17030

Mycophenolic Acid (Mycophenolate Mofetil EP Impurity F)

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Color and Shape: White To Off-White Solid

Molecular weight: 320.34

Ref: 4Z-M-163

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid

Color and Shape: White Powder

Molecular weight: 320.34g/mol

Ref: 54-BI1535

Mycophenolic acid

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Purity: ≥ 98.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 320.34

Ref: 7W-GA8210

Mycophenolic acid 100 µg/mL in Acetonitrile

Controlled Product

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Color and Shape: Single Solution

Molecular weight: 320.34

Ref: 04-A15391000AL-100

(4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid (Mycophenolic Acid)

CAS: 24280-93-1

Color and Shape: Neat

Ref: 86-MM1001.06

Mycophenolic acid

Controlled Product

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Color and Shape: Neat

Molecular weight: 320.34

Ref: 04-C15391000

Mycophenolic Acid

Controlled Product

CAS: 24280-93-1

Applications An antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),

Formula: C₁₇H₂₀O₆

Color and Shape: White To Off-White

Molecular weight: 320.34

Ref: TR-M831500

Mycophenolic Acid-13C-d3

Controlled Product

CAS: 24280-93-1

Applications Mycophenolic Acid-13C-d3 is a labelled Mycophenolic Acid, an antibiotic produced by Penicillium brevi-compactum, P. Stoloniferum and related spp. A selective inhibitor of lymphocyte proliferation by blocking inosine monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of purine nucleotides.
References Senda, M., et al.: Transplantation, 60, 1143 (1995), Nimmesgern, E., et al.: J. Biol. Chem., 271, 19421 (1996), Gummert, J.F., et al.: J. Pharmacol. Exp. Ther., 291, 1100 (1999),

Formula: CC₁₆D₃H₁₇O₆

Color and Shape: Neat

Molecular weight: 324.348

Ref: TR-M831503

Mycophenolate Mofetil EP Impurity F

CAS: 24280-93-1

Formula: C₁₇H₂₀O₆

Molecular weight: 320.34

Ref: ST-EA-CP-M27006

Mycophenolic acid - Bio-X ™

CAS: 24280-93-1

Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. Mycophenolic acid is a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. It has also shown to have antibacterial and antifungal properties.

Formula: C₁₇H₂₀O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 320.34 g/mol

Ref: 3D-BM164624

Mycophenolic Acid

CAS: 24280-93-1

M02087 - Mycophenolic Acid

Formula: C₁₇H₂₀O₆

Purity: 98%

Color and Shape: Solid, White to off-white powder

Molecular weight: 320.341

Ref: 10-M02087

Mycophenolic Acid ((4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic Acid)

CAS: 24280-93-1

Aromatic lactones used as drugs

Formula: C₁₇H₂₀O₆

Color and Shape: White Crystalline Solid

Molecular weight: 320.12599

Ref: 45-1A06830

Mycophenolic acid

CAS: 24280-93-1

Mycophenolic acid is a guanosine monophosphate synthesis pathway blocker. It selectively inhibits inosine monophosphate dehydrogenase (IMPDH) which blocks the conversion of inosine-5-phosphate and xanthine-5-phosphate to guanosine-5-phosphate. This drug inhibits de novo purine biosynthesis. Mycophenolic acid is an immunosuppressant metabolite present in drug formulations that are used to prevent rejections after organ transplants. It has also shown to have antibacterial and antifungal properties.

Formula: C₁₇H₂₀O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 320.34 g/mol

Ref: 3D-FM15781