CAS 24316-19-6: Cephalotaxine
Description:Cephalotaxine is a natural alkaloid derived from the plant genus Cephalotaxus, commonly known as the plum yew. It is characterized by its complex structure, which includes a tetracyclic framework. This compound exhibits a range of biological activities, particularly as an antitumor agent, and has been studied for its potential therapeutic applications in cancer treatment. Cephalotaxine functions by inhibiting cell division, thereby affecting the proliferation of cancer cells. It is known to interact with various cellular pathways, contributing to its cytotoxic effects. The substance is typically found in low concentrations in the plant, necessitating extraction and purification for research and medicinal use. Additionally, cephalotaxine's solubility properties and stability can vary depending on the solvent and environmental conditions, which are important factors to consider in its application and study. As with many alkaloids, safety and toxicity profiles are critical, and handling should be conducted with care in a controlled laboratory environment.
Formula:C18H21NO4
InChI:InChI=1S/C18H21NO4/c1-21-15-9-18-4-2-5-19(18)6-3-11-7-13-14(23-10-22-13)8-12(11)16(18)17(15)20/h7-9,16-17,20H,2-6,10H2,1H3/t16-,17-,18+/m1/s1
InChI key:InChIKey=YMNCVRSYJBNGLD-KURKYZTESA-N
SMILES:OC1C(OC)=CC23N(CCC4=CC=5OCOC5C=C4C12)CCC3
- Synonyms:
- 4H-Cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol, 1,5,6,8,9,14b-hexahydro-2-methoxy-, [1S-(1α,3aS*,14bβ)]-
- Alkaloid A from Cephalotaxus
- Cephalotaxine (8CI)(9CI)
- Nsc 128487
- Nsc 245454
- Nsc 245455
- Zinc 19795976
- [1S-(1α,3aS*,14bβ)]-1,5,6,8,9,14b-Hexahydro-2-methoxy-4H-cyclopenta[a][1,3]dioxolo[4,5-h]pyrrolo[2,1-b][3]benzazepin-1-ol
- (-)-Cephalotaxine
- Cephalotaxine
- See more synonyms