CAS 24345-16-2

Apamin

Description:

Apamin is a neurotoxic peptide derived from the venom of the honeybee (Apis mellifera). It is classified as a small protein, consisting of 18 amino acids, and is known for its ability to selectively block certain types of potassium channels, particularly the SK (small conductance calcium-activated potassium) channels. This action can lead to increased neuronal excitability and has implications in various physiological processes, including neurotransmitter release and muscle contraction. Apamin has garnered interest in pharmacological research due to its potential therapeutic applications, particularly in the treatment of neurological disorders. Its structure features a characteristic disulfide bridge that contributes to its stability and biological activity. Additionally, apamin is soluble in water and exhibits a relatively low molecular weight, which facilitates its interaction with biological membranes. As a research tool, it is often used to study ion channel function and neuronal signaling pathways. However, due to its toxic nature, caution is advised when handling apamin in laboratory settings.

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

InChI: InChI=1/C79H131N31O24S4/c1-35(2)26-49-70(127)107-51-31-136-135-30-41(81)63(120)105-50(28-57(84)114)71(128)108-53(73(130)99-42(12-7-8-22-80)64(121)96-38(5)77(134)110-25-11-15-54(110)75(132)102-47(18-21-58(115)116)69(126)109-59(39(6)111)76(133)95-37(4)62(119)104-49)33-138-137-32-52(106-66(123)44(14-10-24-92-79(88)89)98-65(122)43(13-9-23-91-78(86)87)97-61(118)36(3)94-72(51)129)74(131)101-45(16-19-55(82)112)67(124)100-46(17-20-56(83)113)68(125)103-48(60(85)117)27-40-29-90-34-93-40/h29,34-39,41-54,59,111H,7-28,30-33,80-81H2,1-6H3,(H2,82,112)(H2,83,113)(H2,84,114)(H2,85,117)(H,90,93)(H,94,129)(H,95,133)(H,96,121)(H,97,118)(H,98,122)(H,99,130)(H,100,124)(H,101,131)(H,102,132)(H,103,125)(H,104,119)(H,105,120)(H,106,123)(H,107,127)(H,108,128)(H,109,126)(H,115,116)(H4,86,87,91)(H4,88,89,92)/t36?,37-,38-,39+,41-,42-,43-,44?,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,59?/m0/s1

Apamin

CAS: 24345-16-2

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 2027.3387

Ref: IN-DA0039UY

Apamin

CAS: 24345-16-2

Apamin: 18-amino acid bee venom peptide, blocks SK channels, anti-inflammatory, anti-fibrotic, strongly basic.

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 2027.34

Ref: TM-TP1223

Apamin

CAS: 24345-16-2

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Purity: ≥ 95.0%

Color and Shape: White lyophilised solid

Molecular weight: 2027.37

Ref: 7W-GL2751

Apamin

CAS: 24345-16-2

Apamin

Color and Shape: Solid

Molecular weight: 2,027.34g/mol

Ref: 54-BI4548

Apamin

CAS: 24345-16-2

Please enquire for more information about Apamin including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Purity: Min. 95%

Molecular weight: 2,027.35 g/mol

Ref: 3D-PA16861

Apamin TFA Salt

Controlled Product

CAS: 24345-16-2

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 2027.34 + x(114.02)

Ref: TR-A726115

Apamin

CAS: 24345-16-2

Small Conductance Ca2+-Activated K+ Channel Blocker derived from bee venom (Honeybee, Apis mellifera). This product has disulfide bonds between Cys1-Cys11 and Cys3-Cys15 and is available as a 0.5mg vial.

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Purity: Min. 95%

Molecular weight: 2,027.3 g/mol

Ref: 3D-PAP-4257-V

Apamin

CAS: 24345-16-2

Small Conductance Ca2+-Activated K+ Channel Blocker derived from bee venom

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 2,027.34 g/mol

Ref: 3D-FA73204

Apamin

CAS: 24345-16-2

SK channel blocker

Formula: C₇₉H₁₃₁N₃₁O₂₄S₄

Molecular weight: 2,027.35 g/mol

Ref: 3D-PP49950