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CAS 24365-47-7

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Leupeptin Ac-LL

Description:
Leupeptin Ac-LL, also known as Acetyl-Leu-Leu-Arg, is a synthetic peptide derived from the natural protease inhibitor leupeptin. It is characterized by its ability to inhibit serine and cysteine proteases, making it a valuable tool in biochemical research, particularly in studies involving protein degradation and cellular processes. The compound is typically used to prevent the degradation of proteins during purification and analysis, thereby preserving their functional integrity. Leupeptin Ac-LL is soluble in water and exhibits stability under physiological conditions, although it may be sensitive to extreme pH levels and temperature. Its mechanism of action involves binding to the active sites of proteases, effectively blocking substrate access. This property makes it useful in various applications, including cell culture, enzyme assays, and the study of proteolytic pathways. As with many peptides, care should be taken regarding its storage and handling to maintain its efficacy. Overall, Leupeptin Ac-LL serves as an important reagent in the field of molecular biology and biochemistry.
Formula:C20H38N6O4
InChI:InChI=1/C20H38N6O4/c1-12(2)9-16(24-14(5)28)18(29)26-19(30)17(10-13(3)4)25-15(11-27)7-6-8-23-20(21)22/h11-13,15-17,25H,6-10H2,1-5H3,(H,24,28)(H4,21,22,23)(H,26,29,30)/t15?,16-,17-/m0/s1
InChI key:InChIKey=GDBQQVLCIARPGH-BSOSBYQFSA-N
SMILES:[C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)(C(NC(CCCNC(=N)N)C=O)=O)CC(C)C
Synonyms:
  • (2S)-2-(acetylamino)-N-[(2S)-2-({4-[(diaminomethylidene)amino]-1-formylbutyl}amino)-4-methylpentanoyl]-4-methylpentanamide (non-preferred name)
  • 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide
  • <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-
  • Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-<smallcap>L</span>-leucylargininal
  • Acetyl-L-leucyl-L-leucylargininal
  • L-Leucinamide, N-acetyl-L-leucyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-
  • Leupeptin Ac-LL
  • Leupeptin Hemisulfate From Microbial*Source
  • N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[4-[(aminoiminomethyl)amino]-1-formylbutyl]-<smallcap>L</span>-leucinamide
  • N-Acetyl-L-leucyl-L-leucyl-L-argininal
  • See more synonyms
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Found 2 products.
  • Leupeptin
    Targetmol
    + Info

    Leupeptin

    CAS:
    Leupeptin, from actinomycetes, inhibits various proteases (e.g., trypsin, plasmin, kallikrein, papain, cathepsin B) but not α-chymotrypsin/thrombin.
    Formula:C20H38N6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:426.562

    Ref: TM-T6564L

  • 2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide
    Biosynth
    + Info

    2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide

    CAS:
    2-(2-Acetamido-4-methylvaleramido)-N-(1-formyl-4-guanidinobutyl)-4-methylvaleramide is a synthetic compound that functions as an antifungal agent. It is derived from chemical synthesis, allowing precise modifications for enhanced efficacy. This compound acts by inhibiting vital fungal cell processes, disrupting cell wall synthesis, and impeding protein production, ultimately causing cell death.
    Formula:C20H38N6O4
    Purity:Min. 95%
    Molecular weight:426.6 g/mol

    Ref: 3D-ZAA36547

    50mg
    804.00€
    100mg
    1,211.00€