CAS 2438-57-5

4-fluoroproline

Description:

4-Fluoroproline is a fluorinated derivative of proline, an amino acid that plays a crucial role in protein structure and function. Its chemical structure features a fluorine atom substituted at the fourth carbon of the proline ring, which influences its physical and chemical properties. This modification can affect the molecule's steric and electronic characteristics, potentially altering its interactions in biological systems. 4-Fluoroproline is typically a white crystalline solid and is soluble in polar solvents, such as water and alcohols, due to its polar functional groups. It is often used in biochemical research and pharmaceutical applications, particularly in the study of protein folding and stability, as well as in the design of novel therapeutics. The presence of the fluorine atom can enhance the stability and bioactivity of compounds, making 4-fluoroproline a valuable building block in medicinal chemistry. Additionally, its unique properties allow for the exploration of new pathways in drug development and the synthesis of fluorinated compounds.

Formula: C₅H₈FNO₂

InChI: InChI=1/C5H8FNO2/c6-3-1-4(5(8)9)7-2-3/h3-4,7H,1-2H2,(H,8,9)

SMILES: C1C(CNC1C(=O)O)F

Synonyms:

• Proline, 4-Fluoro-
• (2S,4S)-4-Fluoro-Pyrrolidine-2-Carboxylic Acid
• 4-Fluoroproline
• cis-4-Fluoro-L-Pro-OH
• (S)-4-FLUORO-L-PROLINE
• CIS-4-FLUORO-PROLINE
• L-PROLINE, 4-FLUORO-, (4S)-
• (2S,4S)-4-FLUOROPROLINE
• H-CIS-4-FLUORO-PRO-OH
• CIS-4-FLUORO-PYRROLIDINE-2-CARBOXYLIC ACID
• (2S,4S)-4-Fluoro-pyrrolidine-2-carboxylic acid≥ 97% (NMR)
• H-(2S,4S)-PRO(4-F)-OH
• H-CIS-PRO(4-F)-OH

H-cis-4-Fluoro-Pro-OH

CAS: 2438-57-5

A (4S)-fluoroproline residue replacing the Pro in position Xaa of the (Xaa-Yaa-Gly) collagen repeat prevents triple helix formation.

Formula: C₅H₈FNO₂

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 133.12

Ref: 01-4033274

(2S,4S)-4-FLUORO-2-PYRROLIDINECARBOXYLIC ACID

CAS: 2438-57-5

Formula: C₅H₈FNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 133.1209

Ref: IN-DA0032CH

(2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid

CAS: 2438-57-5

(2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid

Purity: 95%

Molecular weight: 133.12g/mol

Ref: 54-PC5719

(2S,4S)-4-Fluoropyrrolidine-2-carboxylic acid

CAS: 2438-57-5

Formula: C₅H₈FNO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 133.122

Ref: 10-F076031