CAS 2439-04-5

5-Hydroxyisoquinoline

Description:

5-Hydroxyisoquinoline is an organic compound characterized by its isoquinoline structure, which features a fused benzene and pyridine ring system. It possesses a hydroxyl (-OH) group at the 5-position of the isoquinoline ring, contributing to its chemical reactivity and potential biological activity. This compound is typically a pale yellow to brown solid and is soluble in organic solvents, with limited solubility in water. 5-Hydroxyisoquinoline is of interest in medicinal chemistry due to its potential pharmacological properties, including neuroprotective and anti-inflammatory effects. It can participate in various chemical reactions, such as oxidation and substitution, making it a valuable intermediate in organic synthesis. Additionally, its derivatives may exhibit diverse biological activities, which are being explored in research for potential therapeutic applications. As with many organic compounds, handling should be done with care, considering safety data and proper laboratory protocols.

Formula: C₉H₇NO

InChI: InChI=1S/C9H7NO/c11-9-3-1-2-7-6-10-5-4-8(7)9/h1-6,11H

InChI key: InChIKey=CSNXUYRHPXGSJD-UHFFFAOYSA-N

SMILES: OC=1C2=C(C=CC1)C=NC=C2

Synonyms:

• 5-Hydroxyisoquin dine
• 5-Hydroxyisoquinoline90%
• 5-Isoquinolinol
• Isoquinolin-5-Ol
• NSC 51787
• 5-Hydroxyisoquinoline

5-Hydroxyisoquinoline

CAS: 2439-04-5

Formula: C₉H₇NO

Purity: >96.0%(GC)(T)

Color and Shape: White to Gray to Brown powder to crystal

Molecular weight: 145.16

Ref: 3B-H1259

5-Hydroxyisoquinoline

CAS: 2439-04-5

Formula: C₉H₇NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 145.1580

Ref: IN-DA003MSQ

5-Hydroxyisoquinoline

CAS: 2439-04-5

Formula: C₉H₇NO

Purity: 95%

Color and Shape: Liquid

Molecular weight: 145.161

Ref: 10-F076330

5-Hydroxyisoquinoline

CAS: 2439-04-5

5-Hydroxyisoquinoline

Formula: C₉H₇NO

Purity: 95%

Color and Shape: almost white powder

Molecular weight: 145.16g/mol

Ref: 54-OR2817

5-Hydroxyisoquinoline

CAS: 2439-04-5

5-Hydroxyisoquinoline is a quinoline derivative that is synthesized from aziridine. It has been shown to be a potent insulin sensitizing agent in mice with type 2 diabetes mellitus. 5-Hydroxyisoquinoline has been shown to inhibit the activity of purified enzymes preparations and show high selectivity for chloride channels, which are responsible for the transport of chloride ions across cell membranes. This inhibition leads to an influx of protons into the cell, which may lead to a change in the redox potential and changes in the molecular structure of the molecule. The reaction mechanism involves substitution at position 5 of the isoquinoline ring by hydroxy groups (OH).

Formula: C₉H₇NO

Purity: Min. 95%

Color and Shape: Yellow Powder

Molecular weight: 145.16 g/mol

Ref: 3D-FH24373