CAS 244101-02-8

(2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide

Description:

The chemical substance known as (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide, with the CAS number 244101-02-8, is a synthetic organic compound characterized by its complex structure, which includes a propenamide backbone, a sulfonyl group, and multiple aromatic rings. This compound features a bromine atom and a methoxy group on the phenyl ring, contributing to its unique reactivity and potential biological activity. The presence of the naphthalenylmethyl group suggests that it may exhibit significant hydrophobic interactions, influencing its solubility and interaction with biological targets. The sulfonamide functional group is known for its role in medicinal chemistry, often enhancing the compound's pharmacological properties. Overall, this compound may be of interest in research related to drug development, particularly in the fields of oncology or anti-inflammatory therapies, due to its structural features that could interact with specific biological pathways. Further studies would be necessary to elucidate its precise mechanisms of action and potential applications.

Formula: C₂₇H₂₂BrNO₄S

InChI: InChI=1S/C27H22BrNO4S/c1-33-25-14-13-24(28)18-26(25)34(31,32)29-27(30)15-12-21-7-3-5-9-23(21)17-19-10-11-20-6-2-4-8-22(20)16-19/h2-16,18H,17H2,1H3,(H,29,30)/b15-12+

InChI key: InChIKey=ODTKFNUPVBULRJ-NTCAYCPXSA-N

SMILES: C(C1=CC2=C(C=C1)C=CC=C2)C3=C(/C=C/C(NS(=O)(=O)C4=C(OC)C=CC(Br)=C4)=O)C=CC=C3

Synonyms:

• 2-Propenamide, N-[(5-bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-, (2E)-
• CM 9
• L 798106
• GW 671021
• (2E)-N-[(5-Bromo-2-methoxyphenyl)sulfonyl]-3-[2-(2-naphthalenylmethyl)phenyl]-2-propenamide

L-798106

CAS: 244101-02-8

L-798106

Purity: ≥98%

Molecular weight: 536.44g/mol

Ref: 54-BUP08633

L-798106

CAS: 244101-02-8

Formula: C₂₇H₂₂BrNO₄S

Purity: ≥ 99.0%

Color and Shape: White to off-white solid

Molecular weight: 536.44

Ref: 7W-GL1923

L-798106

CAS: 244101-02-8

L-798106 (CM9) is an EP3 receptor antagonist that inhibits EP4, EP1, and EP2 receptors and attenuates PGE2-induced cough.

Formula: C₂₇H₂₂BrNO₄S

Purity: 98.97%

Color and Shape: Solid

Molecular weight: 536.44

Ref: TM-T15689

L-798106

Controlled Product

CAS: 244101-02-8

Formula: C₂₇H₂₂BrNO₄S

Color and Shape: Neat

Molecular weight: 536.437

Ref: TR-L011500

L-798106

CAS: 244101-02-8

L-798106 is a potent and selective h1 receptor antagonist that blocks the action of histamine. It has been shown to inhibit the intracellular calcium concentration, which may be due to its inhibition of myosin phosphatase activity. L-798106 also inhibits cancer cells by interfering with cell growth and preventing the production of cancerous proteins. Interestingly, this drug also has a pressor effect on blood pressure, which may be due to its ability to increase camp levels in the mesenteric artery. L-798106 is an antagonist of epoxyeicosatrienoic acids (EETs) and 2-aminoethoxydiphenyl borate (2-APB). These compounds are potent agonists for the h1 receptor, which causes vasoconstriction and increases in blood pressure. L-798106 has been shown to inhibit protein synthesis at polymerase chain reaction (PCR) levels in prostate cancer cells. This drug also decreases

Formula: C₂₇H₂₂BrNO₄S

Purity: Min. 95%

Molecular weight: 536.44 g/mol

Ref: 3D-UJA10102