CAS 244195-32-2

N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide

Description:

N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide, with the CAS number 244195-32-2, is a synthetic organic compound characterized by its complex structure, which includes a propanamide backbone, a fluorophenyl group, and a piperidine moiety. This compound is notable for its potential pharmacological properties, particularly in the context of central nervous system activity, as it may interact with neurotransmitter systems. The presence of the fluorine atom enhances lipophilicity, potentially influencing its bioavailability and receptor binding affinity. The piperidine ring contributes to its basicity and can affect its pharmacokinetic profile. Additionally, the phenylethyl substituent may play a role in modulating the compound's activity and selectivity towards specific biological targets. Overall, this compound exemplifies the intricate design often seen in drug development, where modifications to the molecular structure can lead to significant changes in biological activity and therapeutic potential.

Formula: C₂₃H₂₉FN₂O

InChI: InChI=1S/C23H29FN2O/c1-18(2)23(27)26(21-10-8-20(24)9-11-21)22-13-16-25(17-14-22)15-12-19-6-4-3-5-7-19/h3-11,18,22H,12-17H2,1-2H3

InChI key: InChIKey=OZDOSQNUJIXEOR-UHFFFAOYSA-N

SMILES: N(C(C(C)C)=O)(C1CCN(CCC2=CC=CC=C2)CC1)C3=CC=C(F)C=C3

Synonyms:

• Propanamide, N-(4-fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-
• 4-Fluoro-Isobutyrylfentanyl
• p-Fluoroisobutyryl fentanyl
• N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide

N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide

Controlled Product

CAS: 244195-32-2

Applications N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide is an impurity of Furanylfentanyl (F864085), which is an opiod analgesic agent and an analog of Fentanyl (F275000). In addition, N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide may be a useful compound for developing fentanyl-conjugated vaccines by utilizing a protein–drug conjugate that generates an in vivo immunoantagonist, which can minimize the concentration of a specific drug at the sites of action.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bremer, P. T., et al.: Angew. Chem. Int. Ed. 55, 3772 (2016); Zernig, G., et al.: Life Sci., 57, 2113 (1995), Bot, G., et al.: J. Pharmacol. Exper. Therap., 285, 1207 (1998)

Formula: C₂₃H₂₉FN₂O

Color and Shape: Neat

Molecular weight: 368.49

Ref: TR-F489575

N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide-d7

Controlled Product

CAS: 244195-32-2

Applications N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide-d7 is deuterium labeled N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide (F489575).N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide is an impurity of Furanylfentanyl (F864085), which is an opiod analgesic agent and an analog of Fentanyl (F275000). In addition, N-(4-Fluorophenyl)-2-methyl-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide may be a useful compound for developing fentanyl-conjugated vaccines by utilizing a protein–drug conjugate that generates an in vivo immunoantagonist, which can minimize the concentration of a specific drug at the sites of action.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bremer, P. T., et al.: Angew. Chem. Int. Ed. 55, 3772 (2016); Zernig, G., et al.: Life Sci., 57, 2113 (1995), Bot, G., et al.: J. Pharmacol. Exper. Therap., 285, 1207 (1998)

Formula: C₂₃H₂₂D₇FN₂O

Color and Shape: Neat

Molecular weight: 375.53

Ref: TR-F489577