CAS 244205-40-1

2-bromophenylboronic acid

Description:

2-Bromophenylboronic acid is an organoboron compound characterized by the presence of a bromine atom and a boronic acid functional group attached to a phenyl ring. Its molecular structure features a phenyl group substituted at the ortho position with a bromine atom and a boronic acid group (-B(OH)2), which is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and alcohols. It is often utilized in Suzuki-Miyaura cross-coupling reactions, which are pivotal in the formation of carbon-carbon bonds. Additionally, 2-bromophenylboronic acid can serve as a building block in the synthesis of pharmaceuticals and agrochemicals. Safety considerations include handling it with care, as boronic acids can be irritants, and proper laboratory protocols should be followed to mitigate exposure.

Formula: C₆H₆BBrO₂

InChI: InChI=1/C6H6BBrO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4,9-10H

SMILES: c1ccc(c(c1)B(O)O)Br

Synonyms:

• 2-Bromobenzeneboronic acid
• O-Bromophenylboronic Acid
• RARECHEM AH PB 0074
• 2-BROMOPHENYLBORONIC ACID
• AKOS BRN-0929
• 2-Bromophenylboronic
• 2-Bromophenylboronic Acid (contains varying amounts of Anhydride)
• 2-Bromobenzeneboronicacid,98%

2-Bromophenylboronic Acid (contains varying amounts of Anhydride)

CAS: 244205-40-1

Formula: C₆H₆BBrO₂

Purity: 97.0 to 110.0 %

Color and Shape: White to Almost white powder to crystal

Molecular weight: 200.83

Ref: 3B-B2889

2-Bromobenzeneboronic acid, 98%

CAS: 244205-40-1

2-Bromobenzeneboronic acid is used to promote greener amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents. This Thermo Scientific Chemicals brand product was originally part of the

Formula: C₆H₆BBrO₂

Purity: 98%

Color and Shape: White to off-white, Powder or crystals or crystalline powder

Molecular weight: 200.83

Ref: 02-L18581

(2-Bromophenyl)boronic acid

CAS: 244205-40-1

Formula: C₆H₆BBrO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 200.8256

Ref: IN-DA003GSR

2-Bromophenylboronic acid

CAS: 244205-40-1

Formula: C₆H₆BBrO₂

Molecular weight: 200.83

Ref: 7W-GK1490

2-Bromobenzeneboronic acid

CAS: 244205-40-1

2-Bromobenzeneboronic acid

Formula: C₆H₆BBrO₂

Purity: 98%

Color and Shape: off-white to faint yellow powder

Molecular weight: 200.83g/mol

Ref: 54-OR10387

2-Bromophenylboronic Acid

Controlled Product

CAS: 244205-40-1

Applications 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
References Ebdrup, S. et al.: Bioorg. Med. Chem. Lett., 13, 2305 (2005);

Formula: C₆H₆BBrO₂

Color and Shape: Neat

Molecular weight: 200.83

Ref: TR-B686945

2-Bromobenzeneboronic acid (contains varying amounts of anhydride)

CAS: 244205-40-1

Formula: C₆H₆BBrO₂

Purity: 95.0%

Color and Shape: Solid, White to very pale yellow crystal powder

Molecular weight: 200.83

Ref: 10-F045258

2-Bromophenylboronic acid

CAS: 244205-40-1

2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors.
2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other.

Formula: C₆H₆BBrO₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 200.83 g/mol

Ref: 3D-FB139186