CAS 24425-13-6

2-(1,1-Dimethylethyl)-1H-benzimidazole

Description:

2-(1,1-Dimethylethyl)-1H-benzimidazole, identified by its CAS number 24425-13-6, is an organic compound that features a benzimidazole core substituted with a tert-butyl group. This compound is characterized by its aromatic structure, which contributes to its stability and potential reactivity. The presence of the tert-butyl group enhances its lipophilicity, making it more soluble in organic solvents compared to water. It typically exhibits properties such as moderate melting and boiling points, and it may show biological activity, which can be of interest in pharmaceutical applications. The compound's structure allows for potential interactions with biological targets, making it a candidate for further research in medicinal chemistry. Additionally, its stability under various conditions makes it suitable for various applications, including as a ligand in coordination chemistry or as an intermediate in organic synthesis. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₁₁H₁₄N₂

InChI: InChI=1/C11H14N2/c1-11(2,3)10-12-8-6-4-5-7-9(8)13-10/h4-7H,1-3H3,(H,12,13)

InChI key: InChIKey=ZQWHWRQRGKZTSE-UHFFFAOYSA-N

SMILES: C(C)(C)(C)C=1NC=2C(N1)=CC=CC2

Synonyms:

• 1H-Benzimidazole, 2-(1,1-dimethylethyl)-
• 1H-Benzimidazole, 2-(1,1-dimethylethyl)- (9CI)
• 2-(1,1-Dimethylethyl)-1H-benzimidazole
• 2-tert-Butyl-1H-1,3-benzodiazole
• 2-tert-butyl-1H-benzimidazole
• Benzimidazole, 2-tert-butyl-
• Brn 0133137
• Nsc 34830
• 5-23-07-00017 (Beilstein Handbook Reference)
• 2-tert-Butylbenzimidazole
• 2-tert-Butylbenzimidazole,97%
• 2-T-BUTYLBENZIMIDAZOLE
• 2-tert-butyl-1H-benzo[d]imidazole
• AKOS BB-3173
• 2-tert-butyl-benzimidazol
• AKOS BBS-00004644

2-tert-Butyl-1H-benzo[d]imidazole

CAS: 24425-13-6

Formula: C₁₁H₁₄N₂

Color and Shape: Solid

Molecular weight: 174.2423

Ref: IN-DA00BCAM

2-tert-Butyl-1H-1,3-benzodiazole

CAS: 24425-13-6

2-tert-Butyl-1H-1,3-benzodiazole (2TBDB) is a methylating agent that belongs to the group of imidazoles. It has been shown to be reactive with both inorganic and organic compounds. 2TBDB can be given orally and has been shown to cause structural changes in the conformation of proteins. Reactive forms of 2TBDB are converted by cytochrome P450 enzymes into pyrazoles, which have been found to inhibit the production of TNF-α induced by lipopolysaccharides (LPS). Pyrazoles such as 2TBDB may also act as hydroxamic acid analogues and act as bond cleavage agents. This mechanism may be responsible for their anti-inflammatory properties. 2TBDB has also been shown to inhibit the production of TNF-α in response to LPS in mice, which may be due to its ability to inhibit TNF-α binding to

Formula: C₁₁H₁₄N₂

Purity: Min. 95%

Molecular weight: 174.24 g/mol

Ref: 3D-ZAA42513