CAS 2443816-45-1

(S)-N-(1-Cyclopropyl-2,2,2-trifluoroethyl)-4-(6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)thiophene-2-carboxamide

CAS: 2443816-45-1

Formula: C₂₂H₁₆F₄N₄OS

Purity: 99%

Color and Shape: Solid

Molecular weight: 460.4473

Ref: IN-DA01V3KJ

ULK-101

CAS: 2443816-45-1

ULK-101

Purity: ≥95%

Molecular weight: 460.45g/mol

Ref: 54-BUP12669

ULK-101

CAS: 2443816-45-1

ULK-101 is a potent and selective ULK1 inhibitor ( IC50s: 8.3/30 nM for ULK1/ULK2). It can suppress autophagy.

Formula: C₂₂H₁₆F₄N₄OS

Purity: 97.55% - 99.94%

Color and Shape: Solid

Molecular weight: 460.45

Ref: TM-T5403

ULK 101

CAS: 2443816-45-1

ULK 101 is a molecule that inhibits autophagy. The research into the ULK-ATG pathway has been mainly focused on its role in cancer, but it is also involved in other diseases such as nematodes. This molecule was designed using computational chemistry and is able to inhibit autophagy selectively by targeting ATG3. ULK 101 has shown anthelmintic activity against nematodes and selectivity for the inhibition of autophagy in mammalian cells.

Formula: C₂₂H₁₆F₄N₄OS

Purity: Min. 95%

Molecular weight: 460.45 g/mol

Ref: 3D-FU172886