CAS 2444364-04-7

Acetamide, 2-[[5-cyano-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-phenyl-2-pyrimidinyl]thio]-N-(6-methyl-2-benzothiazolyl)-

Description:

Acetamide, 2-[[5-cyano-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-phenyl-2-pyrimidinyl]thio]-N-(6-methyl-2-benzothiazolyl)- is a complex organic compound characterized by its unique structural features, which include a thioether linkage and multiple heterocyclic rings. The presence of a cyano group and various aromatic systems contributes to its potential reactivity and biological activity. This compound may exhibit properties typical of amides, such as moderate solubility in polar solvents and the ability to participate in hydrogen bonding. Its intricate structure suggests potential applications in pharmaceuticals or agrochemicals, particularly due to the presence of the pyrazole and pyrimidine moieties, which are often associated with bioactive compounds. Additionally, the benzothiazole group may enhance its interaction with biological targets. As with many synthetic organic compounds, safety and handling precautions should be observed, and its stability under various conditions should be evaluated for practical applications. Further studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₂₆H₂₁N₇OS₂

Synonyms:

• EGFR/HER2/TS-IN-2
• Acetamide, 2-[[5-cyano-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-phenyl-2-pyrimidinyl]thio]-N-(6-methyl-2-benzothiazolyl)-

EGFR/HER2/TS-IN-2

CAS: 2444364-04-7

EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).

Formula: C₂₆H₂₁N₇OS₂

Color and Shape: Solid

Molecular weight: 511.62

Ref: TM-T63532