CAS 2446-83-5

Diisopropyl azodicarboxylate

Description:

Diisopropyl azodicarboxylate (DIAD) is an organic compound characterized by its azodicarboxylate structure, featuring two isopropyl groups attached to the nitrogen atoms of the azole moiety. It is a colorless to pale yellow liquid with a distinctive odor and is known for its role as a reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through various coupling reactions. DIAD is soluble in organic solvents such as dichloromethane and ether but is relatively insoluble in water. It is often used as a mild oxidizing agent and is valued for its ability to facilitate reactions without the need for harsh conditions. Safety considerations include its potential as an irritant and the need for proper handling to avoid exposure. As with many azodicarboxylates, it can decompose under certain conditions, releasing nitrogen gas, which is a characteristic feature of azocompounds. Overall, DIAD is a versatile reagent in synthetic organic chemistry, contributing to the development of complex molecular architectures.

Formula: C₈H₁₄N₂O₄

InChI: InChI=1S/C8H14N2O4/c1-5(2)13-7(11)9-10-8(12)14-6(3)4/h5-6H,1-4H3

InChI key: InChIKey=VVWRJUBEIPHGQF-UHFFFAOYSA-N

SMILES: C(N=NC(OC(C)C)=O)(OC(C)C)=O

Synonyms:

• 1,2-Diazenedicarboxylic acid, 1,2-bis(1-methylethyl) ester
• Azodicarbonic Acid Diisopropyl Ester
• Azodicarboxylic Acid Diisopropyl Ester
• DIAD Alternative to DEAD
• DIISOPYL azodicarboxylate
• Diad
• Diazenedicarboxylic acid, bis(1-methylethyl) ester
• Diisopropyl Azodiformate
• Diisopropyl diazene-1,2-dicarboxylate
• Diisopropyl diazodicarboxylate
• Diisopropylazodicarboxylat
• Diisopropylazodicarboxylate
• Dipropan-2-Yl Diazene-1,2-Dicarboxylate
• Formic acid, azodi-, diisopropyl ester
• Labotest-Bb Lt00454155
• bis(1-methylethyl) (E)-diazene-1,2-dicarboxylate

Diisopropyl Azodicarboxylate (40% in Toluene, ca. 1.9mol/L)

CAS: 2446-83-5

Formula: C₈H₁₄N₂O₄

Color and Shape: Light yellow to Amber to Dark green clear liquid

Molecular weight: 202.21

Ref: 3B-A1246

Diisopropyl azodicarboxylate, 94%

CAS: 2446-83-5

Diisopropyl azodicarboxylate is used as an important reagent in the production of many organic compounds. It is used in association with triphenyl phosphine in Mitsunobu reaction of alcohols, acids and amides. It acts as reactant in the preparation of chromenes resembling classical cannabinoids, nor

Formula: C₈H₁₄N₂O₄

Purity: 94%

Color and Shape: Clear, orange to reddish brown, Liquid

Molecular weight: 202.21

Ref: 02-L10386

Diisopropyl azodicarboxylate

CAS: 2446-83-5

Formula: C₈H₁₄N₂O₄

Purity: 95%

Color and Shape: Liquid

Molecular weight: 202.2078

Ref: IN-DA0034QS

Bis(isopropyl) azodicarboxylate

CAS: 2446-83-5

Bis(isopropyl) azodicarboxylate

Formula: C₈H₁₄N₂O₄

Purity: 98%

Color and Shape: clear. dark orange liquid

Molecular weight: 202.20776g/mol

Ref: 54-OR0923

Diisopropyl azodicarboxylate

CAS: 2446-83-5

Formula: C₈H₁₄N₂O₄

Purity: ≥ 98.0%

Color and Shape: Clear, orange to red-orange liquid

Molecular weight: 202.21

Ref: 7W-GK5790

Diisopropyl azodicarboxylate

CAS: 2446-83-5

Formula: C₈H₁₄N₂O₄

Purity: 99.0%

Color and Shape: Liquid, Clear Liquid

Molecular weight: 202.21

Ref: 10-F044563

Diisopropyl Azodicarboxylate (DIAD)

CAS: 2446-83-5

Formula: C₈H₁₄N₂O₄

Molecular weight: 202.21

Ref: 4Z-A-296002

Diisopropyl azodicarboxylate

CAS: 2446-83-5

Diisopropyl azodicarboxylate is a pyrimidine compound that can be used in the treatment of autoimmune diseases and eye disorders. It is also an important chemical intermediate for pharmaceuticals, such as chemotherapeutic agents. Diisopropyl azodicarboxylate reacts with a nucleophilic group to form a new carbon-nitrogen bond by elimination of nitrogen gas. The reaction mechanism has been studied extensively and is well understood. Diisopropyl azodicarboxylate is a potent inhibitor of many enzymes, including those involved in the synthesis of proteins and phospholipids. It inhibits angiotensin-converting enzyme (ACE), which breaks down angiotensin I into angiotensin II, leading to vasoconstriction. Diisopropyl azodicarboxylate also inhibits receptor molecules that are involved in cell signaling pathways, such as the epidermal growth factor receptor (EGFR).

Formula: C₈H₁₄N₂O₄

Purity: Min. 98 Area-%

Color and Shape: Clear Liquid

Molecular weight: 202.21 g/mol

Ref: 3D-FD05914

Diisopropyl Azodicarboxylate

Controlled Product

CAS: 2446-83-5

Applications Diisopropyl Azodicarboxylate is an azodicarboxylic acid derivative used as a reagent in the production of many organic compounds. Diisopropyl Azodicarboxylate is commonly used as an oxidizer in Mitsunobu reactions and can also serve as a selective deprotectant of N-benzyl groups in the presence of other protecting groups.
References Pichika, R. et al.: Nuc. Med. Biol., 38, 1183 (2011); Kroutil, J. et al.: Synthesis, 3, 446 (2004); Hughes, D.L. et al.: Org. React., 42, 335 (1992);

Formula: C₈H₁₄N₂O₄

Color and Shape: Neat

Molecular weight: 202.21

Ref: TR-D455240

Diisopropyl azodicarboxylate - 40% toluene solution

CAS: 2446-83-5

Diisopropyl azodicarboxylate is a chemical compound that reacts with hydrogen fluoride to form a mixture of diazo and triazole products. The chemical reaction is the first step in the synthesis of many pharmaceuticals, such as penicillin. Diisopropyl azodicarboxylate is used in eye disorders, metabolic disorders, and autoimmune diseases. It has been shown to be effective in treating bowel disease. This drug has been shown to have chemotherapeutic properties, which may be due to its ability to inhibit protein synthesis by binding to the nitrogen atoms on receptor molecules. Diisopropyl azodicarboxylate also reacts with trifluoroacetic acid, forming a disulfide bond that can be analyzed using structural analysis techniques or reaction solution methods.

Formula: C₈H₁₄N₂O₄

Purity: Min. 95%

Color and Shape: Yellow To Yellow Orange Liquid

Molecular weight: 202.21 g/mol

Ref: 3D-FD166028