CAS 2446343-19-5

Palonosetron Impurity 18

CAS: 2446343-19-5

Formula: C₁₉H₂₄N₂O₂

Molecular weight: 312.41

Ref: 4Z-P-5329

6-Hydroxy-(S,S)-Palonosetron

Controlled Product

CAS: 2446343-19-5

Applications 6-Hydroxy-(S,S)-Palonosetron is an intermediate used in the synthesis of 6-Oxo-(S,S)-Palonosetron (O858568), which is an impurity of (S,S)-Palonosetron (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
References Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),

Formula: C₁₉H₂₄N₂O₂

Color and Shape: Neat

Molecular weight: 312.41

Ref: TR-H114855

Palonosetron Impurity 18

CAS: 2446343-19-5

Formula: C₁₉H₂₄N₂O₂

Molecular weight: 312.41

Ref: ST-EA-CP-P14028