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CAS 2448-68-2

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Pipamperone dihydrochloride

Description:
Pipamperone dihydrochloride is a chemical compound primarily recognized for its use as an antipsychotic medication. It belongs to the class of butyrophenones and is characterized by its ability to antagonize dopamine receptors, particularly the D2 subtype, which is significant in the treatment of various psychiatric disorders. The dihydrochloride form indicates that the compound is a salt, enhancing its solubility and stability in pharmaceutical formulations. Pipamperone exhibits a relatively long half-life, allowing for once-daily dosing in clinical settings. Its pharmacological profile includes sedative and anxiolytic properties, making it useful in managing symptoms of schizophrenia and other related conditions. Additionally, it may have effects on other neurotransmitter systems, including serotonin and norepinephrine, contributing to its therapeutic effects. As with many antipsychotics, potential side effects can include sedation, weight gain, and extrapyramidal symptoms, necessitating careful monitoring during treatment. Overall, pipamperone dihydrochloride is an important compound in psychopharmacology, with a well-established role in managing severe mental health disorders.
Formula:C21H30FN3O2·2ClH
InChI:InChI=1S/C21H30FN3O2.2ClH/c22-18-8-6-17(7-9-18)19(26)5-4-12-24-15-10-21(11-16-24,20(23)27)25-13-2-1-3-14-25;;/h6-9H,1-5,10-16H2,(H2,23,27);2*1H
InChI key:InChIKey=BMXXSXQVMCXGJM-UHFFFAOYSA-N
SMILES:C(N)(=O)C1(CCN(CCCC(=O)C2=CC=C(F)C=C2)CC1)N3CCCCC3.Cl
Synonyms:
  • (1,4'-Bipiperidine)-4'-carboxamide, 1'-(3-(p-fluorobenzoyl)propyl)-, dihydrochloride
  • 4'-Carbamoyl-1'-[4-(4-Fluorophenyl)-4-Oxobutyl]-1,4'-Bipiperidinium Dichloride
  • Nsc 170981
  • Pipamperone HCl
  • Pipamperone dichlorhydrate
  • Pipamperone dihydrochloride
  • Pipamperone hydrochloride
  • Piperonil
  • Propitan
  • [1,4′-Bipiperidine]-4′-carboxamide, 1′-[4-(4-fluorophenyl)-4-oxobutyl]-, dihydrochloride
  • [1,4′-Bipiperidine]-4′-carboxamide, 1′-[4-(4-fluorophenyl)-4-oxobutyl]-, hydrochloride (1:2)
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