CAS 2450-71-7

Propargylamine

Description:

Propargylamine is an organic compound characterized by the presence of both an alkyne and an amine functional group. Its chemical formula is C3H5N, indicating it consists of three carbon atoms, five hydrogen atoms, and one nitrogen atom. Propargylamine is a colorless to pale yellow liquid with a distinctive odor. It is known for its reactivity, particularly due to the terminal alkyne group, which can participate in various chemical reactions, including nucleophilic additions and cycloadditions. The amine functionality allows it to engage in hydrogen bonding, influencing its solubility in polar solvents. Propargylamine is utilized in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals, as well as in the development of various chemical intermediates. It is important to handle propargylamine with care, as it can be hazardous, exhibiting irritant properties and potential toxicity. Proper safety measures should be observed when working with this compound in laboratory settings.

Formula: C₃H₅N

InChI: InChI=1S/C3H5N/c1-2-3-4/h1H,3-4H2

InChI key: InChIKey=JKANAVGODYYCQF-UHFFFAOYSA-N

SMILES: C(CN)#C

Synonyms:

• 2-Propyn-1-Amine
• 2-Propynylamine
• 3-Aminoprop-1-yne
• 3-Aminopropyne
• N-(2-Propyn-1-yl)amine
• Nsc 80642
• Prop-2-Inilamina
• Prop-2-Ynylamine
• Prop-2-yn-1-amine
• Prop-2-ynylamin
• Propargyl amine

Propargylamine

CAS: 2450-71-7

Formula: C₃H₅N

Purity: >97.0%(GC)

Color and Shape: Light yellow to Yellow to Orange clear liquid

Molecular weight: 55.08

Ref: 3B-P0911

Propargylamine, 98%

CAS: 2450-71-7

Propargylamine is used in the synthesis of a chiral, a fluorescent macrocycle by 1,3-dipolar cycloaddition of propargyl amides of carbohydrate-linked amino acids and 9,10-bis(azidomethyl)anthracene. It acts as an intermediate in the production of drugs. This Thermo Scientific Chemicals brand product

Formula: C₃H₆ClN

Purity: 98%

Molecular weight: 91.54

Ref: 02-H53495

2-Propyn-1-amine

CAS: 2450-71-7

Formula: C₃H₅N

Purity: 98%

Color and Shape: Liquid

Molecular weight: 55.0785

Ref: IN-DA002OCW

2-Propynylamine

CAS: 2450-71-7

Formula: C₃H₅N

Purity: 97.0%

Color and Shape: Liquid, Clear Liquid

Molecular weight: 55.08

Ref: 10-F307008

Propargylamine

CAS: 2450-71-7

Propargylamine is an irreversible inhibitor that binds to the active site of the enzyme acetylcholinesterase (AChE) and blocks the breakdown of acetylcholine. This leads to increased levels of acetylcholine in the synaptic cleft, which enhances neurotransmission and causes increased muscle contractions. Propargylamine has been shown to be a potent chemotherapy agent against cancer cells, causing neuronal death. It also inhibits epidermal growth factor receptor (EGFR) signaling pathways, leading to decreased tumor cell proliferation. The drug may also have neurotrophic effects by stimulating nerve growth factors or preventing neuronal apoptosis.

Formula: C₃H₅N

Purity: Min. 95%

Color and Shape: Colorless Yellow Clear Liquid

Molecular weight: 55.08 g/mol

Ref: 3D-FP31529

Propargylamine

Controlled Product

CAS: 2450-71-7

Applications A useful intermediates in the preparation of drugs or pesticides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₃H₅N

Color and Shape: Neat

Molecular weight: 55.08

Ref: TR-P762520

Amino-dPEG®12-Tris (dPEG®12-Tris (m-dPEG®11)3)3

CAS: 2450-71-7

Amino-dPEG®12-Tris (dPEG®12-Tris (m-dPEG®11)3)3 is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Amino-dPEG®12-Tris (dPEG®12-Tris (m-dPEG®11)3)3 is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₃H₅N

Purity: Min. 95%

Molecular weight: 55.08 g/mol

Ref: 3D-DPG-5817

Propargyl Amine

CAS: 2450-71-7

Propargyl amine is a biologically active compound that has been shown to induce neuronal death in hl-60 cells. It also inhibits the production of neurotrophic factors and induces the formation of coumarin derivatives. Propargyl amine is structurally related to other known neurotoxic compounds, such as coumarin and pyridine. The mechanism of action is currently unknown, but it may involve interactions with ubiquitin ligases or receptor activity. Propargyl amine was found to be an active analogue for the treatment of skin cancer and has shown good analytical properties for use in quantitative analysis. This product should be stored at room temperature in a dry place away from light in order to avoid chemical degradation.

Purity: Min. 95%

Molecular weight: 55.08 g/mol

Ref: 3D-DPG-5771