CAS 24521-76-4

1,5,6,7-Tetrahydro-6-thioxo-4H-pyrazolo[3,4-d]pyrimidin-4-one

Description:

1,5,6,7-Tetrahydro-6-thioxo-4H-pyrazolo[3,4-d]pyrimidin-4-one is a heterocyclic compound characterized by its unique pyrazolo-pyrimidine structure. This compound features a fused ring system that includes both pyrazole and pyrimidine moieties, contributing to its potential biological activity. The presence of a thioxo group (a sulfur atom double-bonded to a carbon atom) enhances its reactivity and may influence its pharmacological properties. Typically, such compounds are of interest in medicinal chemistry due to their potential as enzyme inhibitors or in the development of therapeutic agents. The compound's molecular structure suggests it may exhibit various interactions with biological targets, making it a candidate for further research in drug development. Additionally, its solubility, stability, and reactivity can vary based on environmental conditions, which are critical factors in its application in pharmaceutical formulations. Overall, 1,5,6,7-Tetrahydro-6-thioxo-4H-pyrazolo[3,4-d]pyrimidin-4-one represents a class of compounds that may hold promise in various chemical and biological applications.

Formula: C₅H₄N₄OS

InChI: InChI=1S/C5H4N4OS/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)

InChI key: InChIKey=SXRSXYWROQWSGJ-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC(=S)N1)NN=C2

Synonyms:

• 1,5,6,7-Tetrahydro-6-thioxo-4H-pyrazolo(3,4-d)pyrimidin-4-one
• 1H-Pyrazolo[3,4-d]pyrimidin-4-ol, 6-mercapto-
• 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione, 6-thio-
• 4H-Pyrazolo[3,4-d]pyrimidin-4-one, 1,5,6,7-tetrahydro-6-thioxo-
• 6-Mercapto-1H-pyrazolo[3,4-d]pyrimidin-4-ol
• 6-thioxo-1,2,5,6-tetrahydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
• B 103U
• NSC 1391
• 4-Hydroxy-6-mercaptopyrazolo[3,4-d]pyrimidine

6-Mercapto-1H,5H,7H-pyrazolo[3,4-d]pyrimidin-4-one

CAS: 24521-76-4

Formula: C₅H₄N₄OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 168.1765

Ref: IN-DA002OEP

6-MERCAPTO-4-HYDROXY-1H-PYRAZOLO[3,4-D]PYRIMIDINE

CAS: 24521-76-4

Formula: C₅H₄N₄OS

Purity: 95%

Molecular weight: 168.17

Ref: 10-F303378

4-Hydroxy-6-mercaptopyrazolo[3,4-d]pyrimidine

CAS: 24521-76-4

4-Hydroxy-6-mercaptopyrazolo[3,4-d]pyrimidine is a pyrimidine compound that is a competitive inhibitor of xanthine oxidase (XO) with an IC50 of 0.5 μM. It binds reversibly to the XO enzyme and reverses the effect of the enzyme, thereby inhibiting the production of uric acid. 4-Hydroxy-6-mercaptopyrazolo[3,4-d]pyrimidine does not bind to any other enzymes in the body or affect serum protein levels, which makes it an ideal drug for patients with gout who are at risk for developing renal failure. The drug has been shown to be effective in animal models and is currently undergoing clinical trials in humans.

Formula: C₅H₄N₄OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 168.18 g/mol

Ref: 3D-FH09751