CAS 24533-72-0

3-[(3S,4S)-9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxophorbin-3-yl]propanoic acid

Description:

The chemical substance known as 3-[(3S,4S)-9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxophorbin-3-yl]propanoic acid, with the CAS number 24533-72-0, is a complex organic compound characterized by its unique structure, which includes a phorbin framework. This compound features multiple substituents, including an ethenyl group and a propanoic acid moiety, contributing to its potential biological activity. The stereochemistry indicated by the (3S,4S) configuration suggests specific spatial arrangements that may influence its interactions with biological systems. The presence of multiple methyl groups and an oxo functional group indicates that it may exhibit lipophilic properties, which could affect its solubility and reactivity. Such compounds are often studied for their roles in biological processes, including photosynthesis and as potential pharmaceuticals. The intricate structure and functional groups suggest that it may participate in various chemical reactions, making it of interest in both synthetic and medicinal chemistry. Further studies would be necessary to elucidate its specific properties and applications.

Formula: C₃₃H₃₄N₄O₃

InChI: InChI=1S/C33H34N4O3/c1-7-19-15(3)23-12-25-17(5)21(9-10-30(39)40)32(36-25)22-11-29(38)31-18(6)26(37-33(22)31)14-28-20(8-2)16(4)24(35-28)13-27(19)34-23/h7,12-14,17,21,34,37H,1,8-11H2,2-6H3,(H,39,40)/b23-12?,24-13-,25-12-,26-14-,27-13?,28-14?,32-22?/t17-,21-/m0/s1

InChI key: InChIKey=IEGUQQKIFBYXLG-JMEOOALISA-N

SMILES: CC=1C2=C3C(=C4[C@@H](CCC(O)=O)[C@H](C)C(=N4)C=C5NC(=CC6=NC(=CC1N3)C(CC)=C6C)C(C=C)=C5C)CC2=O

Synonyms:

• (3S,4S)-9-Ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-3-phorbinepropanoic acid
• 3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, (3S-trans)-
• 3-[(3S,4S)-14-Ethyl-4,8,13,18-tetramethyl-20-oxo-9-vinylphorbin-3-yl]propanoic acid
• 3-phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-
• Pyrophaeophorbid A
• Pyropheophorbide a
• 31,32-Didehydrophytochlorin
• (17S,18S)-3-Vinyl-3-deethyl-17,18-dihydrophytoporphyrin
• 3-Deethyl-3-vinylphytochlorin
• Magnesium pyrophyllate a

3-Phorbinepropanoic acid, 9-ethenyl-14-ethyl-4,8,13,18-tetramethyl-20-oxo-, (3S,4S)-

CAS: 24533-72-0

Formula: C₃₃H₃₄N₄O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 534.6481

Ref: IN-DA002OG8

Pyrophaeophorbid A

CAS: 24533-72-0

Pyrophaeophorbid A

Purity: 95%

Molecular weight: 534.65g/mol

Ref: 54-OR1014870

Pyropheophorbide-a

CAS: 24533-72-0

Formula: C₃₃H₃₄N₄O₃

Purity: 95%

Molecular weight: 534.66

Ref: FT-PPa

Pyropheophorbide-a

CAS: 24533-72-0

Formula: C₃₃H₃₄N₄O₃

Purity: 95%

Molecular weight: 534.66

Ref: FT-PPA

Pyropheophorbide-a

CAS: 24533-72-0

Pyropheophorbide-a (Ppa) shows promise as a photosensitizer in tumor photodynamic therapy (PDT).

Formula: C₃₃H₃₄N₄O₃

Purity: 98.09% - ≥98.0%

Color and Shape: Solid

Molecular weight: 534.65

Ref: TM-T19535

Pyropheophorbide-a

CAS: 24533-72-0

Purity: 97%

Molecular weight: 534.26

Ref: 10-F567303

Pyropheophorbide-a

CAS: 24533-72-0

Pyropheophorbide-a is a photosensitizer that has been shown to induce apoptosis in human osteosarcoma cells and cancer cells. It is also used for the treatment of subcutaneous tumors. Pyropheophorbide-a exhibits photophysical properties and can be activated by light with a wavelength of 630 nm. It has been shown to react with chlorophyll a and other photosensitizers, such as hematoporphyrin derivative, to form reactive oxygen species (ROS) that cause cell death. ROS are generated when the combination of pyropheophorbide-a and hematoporphyrin derivative are excited by light of an appropriate wavelength. ROS react with cellular components such as proteins, DNA, or lipids, causing oxidative damage which may lead to cell death through apoptosis or necrosis. The mechanism underlying the anticancer effects of pyropheophorbide-a is not yet fully understood. The anticancer effects of

Formula: C₃₃H₃₄N₄O₃

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 534.26309

Ref: 3D-FP172350