CAS 245443-52-1

L-Phenylalaninamide,glycyl-L-tyrosyl-L-prolylglycyl-L-lysyl-

Description:

L-Phenylalaninamide, glycyl-L-tyrosyl-L-prolylglycyl-L-lysyl- is a peptide compound characterized by its specific sequence of amino acids. This substance is a derivative of phenylalanine, an essential amino acid, and is part of a larger peptide chain that includes glycine, tyrosine, proline, and lysine. The presence of these amino acids contributes to its structural and functional properties, influencing its solubility, stability, and potential biological activity. Peptides like this one often exhibit unique interactions with biological systems, making them of interest in fields such as biochemistry and pharmacology. The CAS number 245443-52-1 uniquely identifies this compound, facilitating its recognition in scientific literature and databases. While specific applications may vary, compounds of this nature are often explored for their roles in signaling pathways, therapeutic potential, or as research tools in understanding protein interactions and functions. Overall, the characteristics of this peptide suggest a complex interplay of biochemical properties that warrant further investigation.

Formula: C₃₃H₄₆N₈O₇

Synonyms:

• H-Gly-Tyr-Pro-Gly-Lys-Phe-Nh2

PAR-4 (1-6) amide (mouse)

CAS: 245443-52-1

Protease-activated receptor-4 activating peptide derived from murine PAR-4. GYPGKF-amide was able to cause rat platelet aggregation with an EC₅₀ value of 40 µM. Its effect on leucocyte rolling and adherence points at a role of PAR-4 in mediating proinflammatory processes.

Formula: C₃₃H₄₆N₈O₇

Purity: 98.5%

Color and Shape: Whitish Powder

Molecular weight: 666.78

Ref: 01-4035649

H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2

CAS: 245443-52-1

This is a synthetic peptide that mimics the endogenous human epidermal growth factor (EGF) and binds to the toll-like receptor. It has been shown to stimulate physiological function in experimental models of bowel disease and cardiac disease, as well as cancer tissues. The peptide also binds to the guanine nucleotide-binding protein, polymerase chain reaction, and inflammatory bowel disease genes. In vivo studies have confirmed that this peptide enhances the production of EGF in maternal blood and stimulates squamous carcinoma growth in an animal model.

Formula: C₃₃H₄₆N₈O₇

Purity: Min. 95%

Molecular weight: 666.78 g/mol

Ref: 3D-PAR-3672-PI

PAR-4 (1-6) amide (mouse)

CAS: 245443-52-1

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Formula: C₃₃H₄₆N₈O₇

Molecular weight: 666.78 g/mol

Ref: 3D-PP50225

PAR-4 Agonist (Mouse)

CAS: 245443-52-1

Thrombin is the main effector of the coagulation cascade- it is a serine protease. Thrombin binds to active protease activated receptor (PAR) which belongs to a subfamily of G-protein coupled receptors (GPCR). Thrombin activation of mouse PAR-4 reveals an amino terminus sequence of GYPGKF. This is the natural ligand for PAR-4. GYPGKF binds internally to the receptor and leads to signalling activation. Identification of GYPGKF as a PAR-4 agonist has allowed better understand of the function of PAR. Addition of GYPGKF to PAR-4 expressing cell lines achieved 55% of the maximal response of thrombin. GYPGKF can provide understanding of PAR-4 and a template for more potent agonists.

Formula: C₃₃H₄₆N₈O₇

Color and Shape: Powder

Molecular weight: 666.3 g/mol

Ref: 3D-CRB1000559

PAR-4 (1-6) amide (mouse) trifluoroacetate salt

CAS: 245443-52-1

PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2 trifluoroacetate salt is a guanine nucleotide binding protein that belongs to the PAR family of proteins. It is expressed in wild type mice and binds to the cytosolic calcium, which regulates polymerase chain reaction. PAR-4 (1-6) amide (mouse) trifluoroacetate salt H-Gly-Tyr-Pro-Gly-Lys-Phe NH2 trifluoroacetate salt can be used as a potential drug target for epidermal growth factor. It has been shown to activate transcription polymerase chain and transcriptase polymerase chain during transcriptional regulation of messenger RNA.

Formula: C₃₃H₄₆N₈O₇

Purity: Min. 95%

Molecular weight: 666.77 g/mol

Ref: 3D-FP109705

Protease-Activated Receptor-4

CAS: 245443-52-1

Protease-Activated Receptor-4 (PAR4) is a proteinase-activated receptor-4 agonist used in antiplatelet therapy.

Formula: C₃₃H₄₆N₈O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 666.77

Ref: TM-T7380