CAS 24558-91-6

uridine 5'-monophosphomorpholidate

Description:

Uridine 5'-monophosphomorpholidate, with the CAS number 24558-91-6, is a nucleotide derivative characterized by its unique structure, which includes a uridine base linked to a monophosphate group and a morpholidate moiety. This compound is typically used in biochemical research, particularly in the synthesis of RNA and as a building block in the development of nucleic acid analogs. Its morpholidate group enhances the stability of the phosphate linkage, making it useful in various applications, including the study of RNA interactions and the development of therapeutic agents. The compound is generally soluble in polar solvents, which facilitates its use in biochemical assays. Additionally, uridine 5'-monophosphomorpholidate can participate in enzymatic reactions, serving as a substrate for RNA polymerases. Its properties make it a valuable tool in molecular biology, particularly in the fields of genetic engineering and synthetic biology, where precise manipulation of nucleic acids is essential.

Formula: C₁₃H₁₉N₃O₉P.C₁₇H₃₂N₃O

Uridine 5′-Monophosphomorpholidate 4-Morpholine-N,N′-dicyclohexylcarboxamidine Salt-13C, 15N2

Controlled Product

CAS: 24558-91-6

Applications Uridine 5′-Monophosphomorpholidate 4-Morpholine-N,N′-dicyclohexylcarboxamidine Salt-13C, 15N2 is an intermediate in the synthesis of Trilithium UDP-glucuronic Acid-13C1, 15N2 (T886287), which is an isotope labelled analog of Trisodium UDP-glucuronic Acid (T886285). Trisodium UDP-glucuronic Acid is a reactant used in the enzymatic preparation of β-glucuronides.
References Stevenson, D.E., et. al.: Collect Czech. Chem. C., 65, 117 (2000); Robotham, S.A., Brodbelt, J.S.: Biochem. Pharmacol., 82, 1764 (2011); Kren, V., et. al.: Drug Metab. Dispos., 28, 1513 (2000)

Formula: C₁₂CH₂₀NN₂O₉P•C₁₇H₃₁N₃O

Color and Shape: Neat

Molecular weight: 689.72

Ref: TR-U830017

Uridine 5′-Monophosphomorpholidate 4-Morpholine-N,N′-dicyclohexylcarboxamidine Salt

Controlled Product

CAS: 24558-91-6

Applications Uridine 5′-Monophosphomorpholidate 4-Morpholine-N,N′-dicyclohexylcarboxamidine Salt is used in the synthesis of several organic compounds including that of Uridine 5'-(5-thio-α-D-glucopyranosyl pyrophosphate) which is a potent activator of rat liver glycogen synthetase. It was used as a reagent in glycoprotein labelling with click chemistry and carbohydrate detection. Also used in the preparation of UDP-3-O[R-3-Hydroxymyristoyl]-N-acetylglucosamine Tris Salt (U250525).
References Graham, T., et al., Biochemistry-US, 15, 1189 (1976); Wu, Z., et al.: Carbohyd. Res., 412, 1 (2015);

Formula: C₁₃H₂₀N₃O₉P·(C₁₇H₃₁N₃O)

Color and Shape: Neat

Molecular weight: 686.7

Ref: TR-U830015

Uridine 5′-monophosphomorpholidate 4-morpholine-N,N′-dicyclohexylcarboxamidine

CAS: 24558-91-6

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Formula: C₁₇H₃₁N₃O•C₁₃H₂₀N₃O₉P

Purity: Min. 95%

Molecular weight: 686.74 g/mol

Ref: 3D-FU183502