CAS 2457-76-3

4-Amino-2-chlorobenzoic acid

Description:

4-Amino-2-chlorobenzoic acid, with the CAS number 2457-76-3, is an aromatic amino acid derivative characterized by the presence of both an amino group (-NH2) and a carboxylic acid group (-COOH) on a chlorinated benzene ring. This compound features a chlorine atom located at the second position and an amino group at the fourth position of the benzoic acid structure. It is typically a white to off-white crystalline solid that is soluble in water and polar organic solvents. The presence of the amino and carboxylic acid functional groups imparts acidic and basic properties, allowing it to participate in various chemical reactions, including amide formation and electrophilic substitution. 4-Amino-2-chlorobenzoic acid is often used in organic synthesis, as an intermediate in the production of dyes, pharmaceuticals, and agrochemicals. Additionally, it may exhibit biological activity, making it of interest in medicinal chemistry and research applications. Proper handling and safety measures should be observed due to its potential reactivity and toxicity.

Formula: C₇H₆ClNO₂

InChI: InChI=1S/C7H6ClNO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,9H2,(H,10,11)

InChI key: InChIKey=MBDUKNCPOPMRJQ-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(Cl)C=C(N)C=C1

Synonyms:

• 2-Chloro-4-Aminobenzoic Acid
• 2-Chloro-p-aminobenzoic acid
• 4-Amino-2-Chlorobenzoate
• 4-Amino-3-trifluoromethyl benzoic acid
• Benzoic acid, 4-amino-2-chloro-
• NSC 33944
• NSC 53160
• NSC 64328
• o-Chloro-p-aminobenzoic acid
• 4-Amino-2-chlorobenzoic acid

4-Amino-2-chlorobenzoic Acid

CAS: 2457-76-3

Formula: C₇H₆ClNO₂

Purity: >97.0%(T)

Color and Shape: White to Light red to Green powder to crystal

Molecular weight: 171.58

Ref: 3B-A0951

4-Amino-2-chlorobenzoic acid, 98%

CAS: 2457-76-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₆ClNO₂

Purity: 98%

Color and Shape: Pale cream to cream to pale brown, Crystals or powder or crystalline powder

Molecular weight: 171.58

Ref: 02-A10116

Benzoic acid, 4-amino-2-chloro-

CAS: 2457-76-3

Formula: C₇H₆ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 171.5810

Ref: IN-DA002OLQ

4-Amino-2-chlorobenzoic acid

CAS: 2457-76-3

Formula: C₇H₆ClNO₂

Molecular weight: 171.58

Ref: 7W-GM8360

4-Amino-2-chlorobenzoic acid

CAS: 2457-76-3

4-Amino-2-chlorobenzoic acid

Formula: C₇H₆ClNO₂

Purity: 98%

Color and Shape: off-white solid

Molecular weight: 171.58g/mol

Ref: 54-OR914371

4-Amino-2-chlorobenzoic Acid

CAS: 2457-76-3

Formula: C₇H₆ClNO₂

Molecular weight: 171.58

Ref: 4Z-B-085224

4-Amino-2-chlorobenzoic Acid

Controlled Product

CAS: 2457-76-3

Formula: C₇H₆ClNO₂

Color and Shape: Neat

Molecular weight: 171.58

Ref: TR-A603270

4-Amino-2-chlorobenzoic acid

CAS: 2457-76-3

4-Amino-2-chlorobenzoic acid (4ACB) is a drug that inhibits the absorption of other drugs by binding to their active sites. It is used as an analytical reagent in chromatographic methods for determining protein concentration, and has been shown to be effective in reducing pain in animal models. 4ACB has also been shown to have ochronotic properties, which may be due to its ability to inhibit the formation of reactive oxygen species. 4ACB binds with high affinity to the plasma proteins albumin and alpha1-acid glycoprotein, with a binding constant of 10-8 M. The elimination half-life of 4ACB is approximately 27 hours, and it is excreted primarily through the kidneys.

Formula: C₇H₆ClNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 171.58 g/mol

Ref: 3D-FA05821

4-Amino-2-chlorobenzoic acid - 98%

CAS: 2457-76-3

4-Amino-2-chlorobenzoic acid (4ACBA) is a pharmaceutical chemical that is used in the preparation of pharmaceutical preparations. 4ACBA has been shown to be absorbed through the maternal blood and have an inhibitory effect on rat sciatic nerve. The uptake of 4ACBA was found to be dose dependent, with a maximum concentration reached after 30 minutes. The pharmacokinetic properties of 4ACBA have been shown to be nonlinear, with plasma concentrations decreasing as dosage increases.

Formula: C₇H₆ClNO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 171.58 g/mol

Ref: 3D-FA164888

4-Amino-2-chlorobenzoic acid

CAS: 2457-76-3

Formula: C₇H₆ClNO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 171.58

Ref: 10-F033228