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CAS 2459302-76-0

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Tofacitinib N-hydroxy iMpurity

Description:
Tofacitinib N-hydroxy impurity, identified by the CAS number 2459302-76-0, is a chemical compound related to tofacitinib, a Janus kinase inhibitor used primarily in the treatment of autoimmune diseases such as rheumatoid arthritis. This impurity is characterized by the presence of a hydroxyl group (-OH) attached to the tofacitinib structure, which may influence its pharmacological properties and stability. The presence of such impurities is significant in pharmaceutical formulations, as they can affect the efficacy, safety, and overall quality of the drug. Typically, impurities are monitored and controlled during the drug development process to ensure compliance with regulatory standards. The characterization of this impurity involves techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to determine its structure and concentration. Understanding the properties and behavior of impurities like tofacitinib N-hydroxy is crucial for ensuring the safety and effectiveness of the final pharmaceutical product.
Formula:C13H19N5O
Synonyms:
  • Tofacitinib N-hydroxy iMpurity
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