CAS 24603-63-2

1,2-Benzisoxazol-3(2H)-one,5-chloro-

Description:

1,2-Benzisoxazol-3(2H)-one, 5-chloro- is a heterocyclic organic compound characterized by its fused benzene and isoxazole rings. The presence of a chlorine atom at the 5-position of the isoxazole ring influences its chemical reactivity and physical properties. This compound typically exhibits a crystalline solid form and is soluble in organic solvents, which may include alcohols and ethers, but has limited solubility in water. It is often utilized in medicinal chemistry and research due to its potential biological activities, including antimicrobial and anti-inflammatory properties. The structure of this compound allows for various substitution reactions, making it a versatile intermediate in organic synthesis. Additionally, its unique electronic properties, derived from the conjugated system of the aromatic and heterocyclic components, contribute to its reactivity and interaction with biological targets. Safety data should be consulted for handling and usage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₇H₄ClNO₂

Synonyms:

• 1,2-Benzisoxazol-3-ol,5-chloro- (7CI,8CI)
• 5-Chloro-3-benzisoxazolinone
• 5-Chloro-3-hydroxybenzisoxazole
• 5-Chlorobenzo[d]isoxazole-3-one
• 5-Chloro-1,2-benzisoxazol-3(2H)-one
• 1,2-Benzisoxazol-3(2H)-one, 5-chloro-
• 5-Chlorobenzo[d]isoxazol-3-ol, 97%
• 5-chloro-2,3-dihydro-1,2-benzoxazol-3-one
• 5-chloro-1,2-benzoxazol-3-ol
• 5-chlorobenzo[d]isoxazol-3(2H)-one

1,2-Benzisoxazol-3(2H)-one, 5-chloro-

CAS: 24603-63-2

Formula: C₇H₄ClNO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 169.5652

Ref: IN-DA002OQL

5-Chloro-3-hydroxybenzisoxazole

CAS: 24603-63-2

5-Chloro-3-hydroxybenzisoxazole

Purity: 97%

Molecular weight: 169.57g/mol

Ref: 54-OR1005954

5-CHLORO-2,3-DIHYDRO-1,2-BENZOXAZOL-3-ONE

CAS: 24603-63-2

Purity: 97%

Molecular weight: 169.5599976

Ref: 10-F838960

5-Chloro-1,2-benzoxazol-3-ol

CAS: 24603-63-2

5-Chloro-1,2-benzoxazol-3-ol is a molecule with analgesic properties. It was shown to inhibit the activity of nociceptive neurons in the rat spinal cord. The mechanism of action is thought to be similar to that of MK-801, which enhances the effects of glutamate on excitatory amino acid receptors and inhibits NMDA receptors. 5-Chloro-1,2-benzoxazol-3-ol may act as an antagonist at GABAergic synapses. 5-Chloro-1,2-benzoxazol-3-ol binds to the benzoate site on GABA A receptors and reduces the duration of chloride ion channel opening. This prevents chloride ions from entering nerve cells and hyperpolarizes them. This results in less action potentials being generated and therefore reduced pain sensation. 5-(chloro)-1,2 benzoxazole 3(4H)-one can

Formula: C₇H₄ClNO₂

Purity: Min. 95%

Molecular weight: 169.56 g/mol

Ref: 3D-ZAA60363