CAS 246256-50-8

5(6)-carboxytetramethylrhodamine N-suc-cinimidyl ester

Description:

5(6)-Carboxytetramethylrhodamine N-succinimidyl ester, commonly referred to as TMR-OSu, is a fluorescent dye widely used in bioconjugation and labeling applications in biochemical research. This compound features a rhodamine core, which is known for its strong fluorescence properties, particularly in the green to red spectrum. The presence of a carboxyl group enhances its solubility in aqueous solutions, while the N-succinimidyl ester moiety allows for efficient coupling to amine-containing biomolecules, such as proteins and peptides. This reactivity is crucial for creating stable conjugates that can be used in various applications, including fluorescence microscopy, flow cytometry, and other imaging techniques. TMR-OSu is characterized by its high quantum yield and photostability, making it an excellent choice for long-term studies. Additionally, its ability to provide a bright signal enables sensitive detection of target molecules in complex biological samples. Overall, TMR-OSu is a versatile tool in the field of molecular biology and biochemistry for studying protein interactions and cellular processes.

Formula: C₂₉H₂₅N₃₀₇

InChI: InChI=1/C29H25N3O7/c1-30(2)17-6-9-21-23(14-17)37-24-15-18(31(3)4)7-10-22(24)29(21)20-8-5-16(13-19(20)28(36)38-29)27(35)39-32-25(33)11-12-26(32)34/h5-10,13-15H,11-12H2,1-4H3

SMILES: CN(C)c1ccc2c(c1)Oc1cc(ccc1C12c2ccc(cc2C(=O)O1)C(=O)ON1C(=O)CCC1=O)N(C)C

Synonyms:

• 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester
• (2,5-Dioxopyrrolidin-1-Yl) 3',6'-Bis(Dimethylamino)-3-Oxo-Spiro[Isobenzofuran-1,9'-Xanthene]-5-Carboxylate
• 5(6)-Carboxytetramethylrhodamine Succinimidyl Ester
• 9-[2-Carboxy-4(or 5)-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-3,6-bis(dimethylamino)-xanthylium inner salt
• 5(6)-Tamra,Se
• 5(6)-TAMRA,SE, >95%
• 5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester, mixed isomers
• 5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester] *Mixed isomers*
• 5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester
• 5(6)-Carboxytetramethylrhodamine succinimidyl ester - Mixture of 2 isomers
• 5(6)-TAMRA, SE [5-(and-6)-Carboxytetramethylrhodamine, succinimidyl ester] *CAS 246256-50-8*
• 5(6)-TAMRA-SEor5(6)-TAMRA-NHS

Xanthylium, 9-[2-carboxy-4(or 5)-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-3,6-bis(dimethylamino)-, inner salt

CAS: 246256-50-8

Formula: C₃₀H₂₉N₃O₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 543.5672

Ref: IN-DA002OU7

5(6)-Tamra Se

CAS: 246256-50-8

5(6)-Tamra Se

Purity: 95%(isomer mixture)

Molecular weight: 527.52g/mol

Ref: 54-OR1023790

5(6)-TAMRA SE

CAS: 246256-50-8

5(6)-TAMRA SE

Purity: ≥95%

Molecular weight: 527.53g/mol

Ref: 54-BUP06496

5(6)-TAMRA SE

CAS: 246256-50-8

5(6)-TAMRA SE (5(6)-Carboxytetramethylrhodamine N-succinimidyl ester) is the amine-reactive, mixed isomer form of TAMRA.

Formula: C₂₉H₂₅N₃O₇

Purity: 95%

Color and Shape: Solid

Molecular weight: 527.53

Ref: TM-T18898

5(6)-Carboxytetramethylrhodamine succinimidyl ester - Mixture of 2 isomers

CAS: 246256-50-8

5(6)-Carboxytetramethylrhodamine succinimidyl ester is a chemical that can be used as a research chemical, speciality chemical, or a building block in the synthesis of other compounds. It is a high quality product and has been shown to be useful in the synthesis of complex compounds. This compound reacts with amines to form N-hydroxysuccinimide esters and is an excellent reagent for the production of fluorescamine derivatives. 5(6)-Carboxytetramethylrhodamine succinimidyl ester is also an excellent scaffold for the production of other chemicals such as peptides, proteins, and drugs. CAS No: 246256-50-8

Formula: C₂₉H₂₅N₃O₇

Purity: Min. 95%

Color and Shape: Red Powder

Molecular weight: 527.52 g/mol

Ref: 3D-FC45652

5(6)-TAMRA SE

CAS: 246256-50-8

Purity: 99%

Molecular weight: 1054.34

Ref: 10-F567302

5(6)-Carboxytetramethylrhodamine Succinimidyl Ester (Technical Grade)

Controlled Product

CAS: 246256-50-8

Applications 5(6)-Carboxytetramethylrhodamine Succinimidyl Ester is a fluorescent labeling reagent suitable for labeling antibody and nucleic acids. It exhibits excitation and emission at 542 nm and 575 nm, respectively. 5(6)-Carboxytetramethylrhodamine Succinimidyl Ester can be used for in vivo imaging applications.
References Kanduluru, A. K., et al.: Bioconjugate Chem. 27, 2157 (2016); Pradipta, A. R., et al.: ACS Sens 1, 623 (2016)

Formula: C₂₄H₂₂N₂O₃·C₆H₇NO₄

Color and Shape: Neat

Molecular weight: 543.567

Ref: TR-C182650