CAS 2465-59-0

Oxypurinol

Description:

Oxypurinol is a chemical compound that serves as a metabolite of allopurinol, primarily used in the treatment of gout and hyperuricemia. It is classified as a xanthine oxidase inhibitor, which helps to reduce uric acid levels in the body by inhibiting the enzyme responsible for its production. The molecular formula of oxypurinol is C5H4N4O3, and it has a molecular weight of approximately 168.11 g/mol. This compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a slightly acidic pH. Oxypurinol's mechanism of action involves the competitive inhibition of xanthine oxidase, leading to decreased synthesis of uric acid from purines. It is important to monitor patients for potential side effects, which may include skin rashes or gastrointestinal disturbances. Overall, oxypurinol is an effective therapeutic agent for managing conditions associated with elevated uric acid levels, contributing to improved patient outcomes in gout management.

Formula: C₅H₄N₄O₂

InChI: InChI=1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)

InChI key: InChIKey=HXNFUBHNUDHIGC-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC(=O)N1)NN=C2

Synonyms:

• 1H,3H,9H-Alloxanthine
• 1H,4H,5H,6H,7H-Pyrazolo[3,4-d]pyrimidine-4,6-dione
• 1H-Pyrazolo[3,4-d]pyrimidin-4,6-diol
• 1H-Pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
• 1H-pyrazolo[3,4-d]pyrimidine-4,6(2H,5H)-dione
• 1H-pyrazolo[3,4-d]pyrimidine-4,6-diol
• 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine
• 4,6-Dioxopyrazolo[3,4-d]pyrimidine
• 4H-Pyrazolo[3,4-d]pyrimidine-4,6(5H)-dione, 1,7-dihydro-
• Alloxanthin
• Alloxanthine
• Bw 55-5
• NSC 76239
• Oxoallopurinol
• Oxyprim
• Oxypurinol

4,6-Dihydroxy-1H-pyrazolo[3,4-d]pyrimidine, 98+%

CAS: 2465-59-0

4,6-Dihydroxy-1H-pyrazolo[3,4-d]pyrimidine is an inhibitor to study the specificity and kinetics of xanthine oxidase. It is also used as an anti-inflammatory agent via inhibition of xanthine oxidase. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfo

Formula: C₅H₄N₄O₂

Purity: 98+%

Color and Shape: Powder, White to cream

Molecular weight: 152.11

Ref: 02-L07160

4,6-Dihydroxypyrazolo[3,4-d]pyrimidine

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 152.1109

Ref: IN-DA002OY2

Oxypurinol

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Molecular weight: 152.11

Ref: 7W-GL6922

Oxypurinol

CAS: 2465-59-0

Oxypurinol

Purity: ≥98%

Molecular weight: 152.11g/mol

Ref: 54-BUP11857

Oxypurinol-13C3-15N3

CAS: 2465-59-0

Formula: C₂₁₃C₃H₄N₁₅N₃O₂

Color and Shape: Off-White Solid

Molecular weight: 158.07

Ref: 4Z-A-6914

Oxypurinol

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Color and Shape: White To Off-White Solid

Molecular weight: 152.11

Ref: 4Z-A-693

Oxypurinol

Controlled Product

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Color and Shape: Neat

Molecular weight: 152.11

Ref: 04-C15811500

Oxypurinol 100 µg/mL in Water

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Color and Shape: Single Solution

Molecular weight: 152.11

Ref: 04-A15811500WA-100

Oxypurinol

Controlled Product

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Color and Shape: Neat

Molecular weight: 152.11

Ref: 86-MM0034.07

1H-Pyrazolo[3,4-d]pyrimidine-4,6-diol

CAS: 2465-59-0

1H-Pyrazolo[3,4-d]pyrimidine-4,6-diol

Formula: C₅H₄N₄O₂

Purity: 95%

Color and Shape: pale-yellow solid

Molecular weight: 152.11g/mol

Ref: 54-OR18615

Oxypurinol

CAS: 2465-59-0

Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure.

Formula: C₅H₄N₄O₂

Purity: 99.793% - >99.99%

Color and Shape: Solid

Molecular weight: 152.11

Ref: TM-T1694

4,6-Dihydroxypyrazolo[3,4-d]pyrimidine

Controlled Product

CAS: 2465-59-0

Stability Hygroscoipic
Applications 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a major metabolite of Allopurinol (A547300). It is a xanthine oxidase inhibitor.
References Pacher, P., et al.: Pharmacol. Rev., 58, 87 (2006); Marro, P., et al.: Brain Res., 650, 9 (1994); Abramov, A., et al.: J. Neurosci., 27, 1129 (2007); Day, R., et al.: Clin. Pharmacokinet., 46, 623 (2007);

Formula: C₅H₄N₄O₂

Color and Shape: Off White Solid

Molecular weight: 152.11

Ref: TR-D454550

1H,2H,4H,5H,6H-pyrazolo[3,4-d]pyrimidine-4,6-dione

CAS: 2465-59-0

Purity: 98%

Molecular weight: 152.11

Ref: 10-F793773

4,6-Dihydroxy-1H-pyrazolo[3,4-d]pyrimidine

CAS: 2465-59-0

4,6-Dihydroxypyrazolo[3,4-d]pyrimidine is a xanthine derivative that is used as a therapeutic agent. It has inhibitory properties against xanthine oxidase and other enzymes. 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine inhibits the activity of xanthine oxidase by covalent bonding to the iron atom in the enzyme's active site. This binding prevents the conversion of hypoxanthine to xanthine and subsequently prevents the conversion of xanthine to uric acid. The resulting accumulation of hypoxanthine can lead to bowel disease. 4,6-Dihydroxypyrazolo[3,4-d]pyrimidine has also been shown to be toxic when administered orally in large doses or injected intravenously in small doses because it binds to matrix proteins and causes epidermal necrosis.

Formula: C₅H₄N₄O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 152.11 g/mol

Ref: 3D-FD00465

Oxypurinol

CAS: 2465-59-0

Formula: C₅H₄N₄O₂

Molecular weight: 152.11

Ref: ST-EA-CP-A12012