CAS 24696-26-2
:C16-Ceramide
Description:
C16-Ceramide, also known as N-hexadecanoyl sphingosine, is a type of sphingolipid that plays a crucial role in cellular structure and signaling. It is characterized by a long-chain fatty acid (hexadecanoic acid) linked to a sphingosine backbone, which contributes to its amphiphilic nature, allowing it to interact with both hydrophilic and hydrophobic environments. This ceramide is primarily found in the lipid bilayers of cell membranes, where it contributes to membrane stability and fluidity. C16-Ceramide is also involved in various biological processes, including cell signaling, apoptosis, and the regulation of cell growth and differentiation. Its presence in the skin is significant for maintaining barrier function and hydration. Additionally, ceramides are studied for their potential therapeutic applications in skin disorders and other health conditions. Due to its structural properties, C16-Ceramide can also influence the formation of lipid rafts and play a role in the pathophysiology of certain diseases, making it a subject of interest in both biochemistry and pharmacology.
Formula:C34H67NO3
InChI:InChI=1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1
InChI key:InChIKey=YDNKGFDKKRUKPY-TURZORIXSA-N
SMILES:[C@@H](NC(CCCCCCCCCCCCCCC)=O)([C@@H](/C=C/CCCCCCCCCCCCC)O)CO
Synonyms:- (2S,3R,4E)-2-N-Palmitoyloctadecasphinga-4-ene
- 24696-26-2
- <span class="text-smallcaps">D</span>-erythro-C<sub>16</sub>-Ceramide
- <span class="text-smallcaps">D</span>-erythro-N-Hexadecanoylsphingenine
- <span class="text-smallcaps">D</span>-erythro-N-Palmitoylsphingosine
- <span class="text-smallcaps">D</span>-erythro-Δ<sup>4</sup>-Ceramide
- C16-Ceramide
- C16:0-Ceramide
- C<sub>16</sub>-Ceramide
- Ceramide (d18:1,C16:0)
- Ceramide 16
- Ceramide d18:1/16:0
- Hexadecanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
- Hexadecanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-
- Hexadecanamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, [R-[R*,S*-(E)]]-
- N-Hexadecanoyl-<span class="text-smallcaps">D</span>-erythro-ceramide
- N-Hexadecanoylsphingosine
- N-Palmitoyl 4-sphingenine
- N-Palmitoyl ceramide
- N-Palmitoyl-<span class="text-smallcaps">D</span>-erythro-sphingosine
- N-Palmitoyl-<span class="text-smallcaps">D</span>-sphingosine
- N-Palmitoylsphingosine
- N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]hexadecanamide
- N-[(4E)-1,3-Dihydroxy-4-octadecen-2-yl]hexadecanamid
- N-[(4E)-1,3-Dihydroxy-4-octadecen-2-yl]hexadecanamide
- See more synonyms
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C16 Ceramide
CAS:C16 CeramideFormula:C34H67NO3Purity:≥95%Color and Shape:Solid-PowderMolecular weight:537.90067C16 Ceramide
CAS:C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.Formula:C34H67NO3Purity:99% - 99.72%Color and Shape:White Crystalline SolidMolecular weight:537.90C16-Ceramide
CAS:N-((2S,3R,E)-1,3-Dihydroxyoctadec-4-en-2-yl)palmitamideFormula:C34H67NO3Purity:99%Molecular weight:537.9C16-Ceramide
CAS:Applications A predominant, rather hydrophobic natural ceramide. Activates a cytosolic serine/threonine protein phosphatase in T9 cells; induces EGF receptor phosphorylation in A-431 cells; stimulates ceramide-activated protein kinase.
References Shoyama, Y., et al.: J. Lipid Res., 19, 250 (1978), Mathias, S., et al.: Proc. Natl. Sci. USA, 88, 10009 (1991), Dobrowsky, R.T., et al.: J. Biol. Chem., 267, 5048 (1992)Formula:C34H67NO3Color and Shape:NeatMolecular weight:537.9C16-Ceramide-13C2,d2
CAS:Controlled ProductFormula:C2C32D2H65NO3Color and Shape:NeatMolecular weight:541.898C16-Ceramide-13C3-15N
CAS:Controlled ProductFormula:C3C31H6715NO3Color and Shape:NeatMolecular weight:541.872
