CAS 24697-74-3

Leonurine

Description:

Leonurine, with the CAS number 24697-74-3, is a naturally occurring alkaloid primarily derived from the plant Leonurus cardiaca, commonly known as motherwort. This compound is characterized by its structural features, which include a pyridine ring and a phenolic hydroxyl group, contributing to its biological activity. Leonurine is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. It has been studied for its possible applications in traditional medicine, particularly in the treatment of cardiovascular and neurological disorders. Additionally, leonurine exhibits mild sedative effects, which may be beneficial for anxiety and stress relief. Its solubility in water is limited, which can affect its bioavailability and therapeutic efficacy. As research continues, the full spectrum of its effects and mechanisms of action is being explored, highlighting the importance of natural compounds in drug development and therapeutic applications.

Formula: C₁₄H₂₁N₃O₅

InChI: InChI=1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)

InChI key: InChIKey=WNGSUWLDMZFYNZ-UHFFFAOYSA-N

SMILES: C(OCCCCNC(=N)N)(=O)C1=CC(OC)=C(O)C(OC)=C1

Synonyms:

• 24697-74-3
• 4-Carbamimidamidobutyl 4-Hydroxy-3,5-Dimethoxybenzoate Hydrochloride Hydrate
• 4-Carbamimidamidobutyl-4-hydroxy-3,5-dimethoxybenzolcarboxylat
• 4-Guanidino-1-butanol Syringate
• 4-Hydroxy-3,5-dimethoxybenzoic Acid 4-[(Aminoiminomethyl)amino]butyl Ester
• 4-Hydroxy-3,5-dimethoxybenzoic Acid d-Guanidinobutyl Ester
• 4-[(Diaminomethylidene)Amino]Butyl 4-Hydroxy-3,5-Dimethoxybenzoate
• Benzoic Acid, 4-Hydroxy-3,5-Dimethoxy-, 4-[(Aminoiminomethyl)Amino]Butyl Ester
• Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ester with (4-hydroxybutyl)guanidine
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate
• Guanidine, (4-hydroxybutyl)-, 4-hydroxy-3,5-dimethoxybenzoate (ester)
• Leonurin
• Leonurine
• Scm 198
• Syringic Acid d-Guanidinobutyl Ester

Benzoic acid, 4-hydroxy-3,5-dimethoxy-, 4-[(aminoiminomethyl)amino]butyl ester

CAS: 24697-74-3

Formula: C₁₄H₂₁N₃O₅

Purity: %

Color and Shape: Solid

Molecular weight: 311.3336

Ref: IN-DA002P1O

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

CAS: 24697-74-3

4-Guanidinobutyl 4-Hydroxy-3,5-Dimethoxybenzoate

Purity: 99%

Molecular weight: 311.33g/mol

Ref: 54-OR1027299

Leonurine

CAS: 24697-74-3

Formula: C₁₄H₂₂CLN₃O₅

Molecular weight: 347.80

Ref: 7W-GY7471

Leonurine

CAS: 24697-74-3

Leonurine

Purity: ≥98%

Molecular weight: 311.33g/mol

Ref: 54-BUP10292

Leonurine

CAS: 24697-74-3

Leonurine hydrochloride has anti-oxidative, anti-inflammatory, and antitumor activities, it exerts antidiabetic, cardiovascular, and bovine mastitis protection, it has an inhibitory effect on bleeding caused by incomplete abortion. Leonurine hydrochloride increases the expression levels of caspase-3, caspase-9 and Bax/Bcl-2, and it inhibits osteoclastogenesis and prevent osteoporosis associated with estrogen deficiency by inhibiting the NF-κB and PI3K/Akt signaling pathways.

Formula: C₁₄H₂₁N₃O₅

Purity: 95%~99%

Molecular weight: 311.338

Ref: BP-BP0850

Leonurine

CAS: 24697-74-3

Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.

Formula: C₁₄H₂₁N₃O₅

Purity: 98.55%

Color and Shape: White Crystalline Powder

Molecular weight: 311.33

Ref: TM-T5S2102

Leonurine

CAS: 24697-74-3

Formula: C₁₄H₂₁N₃O₅

Purity: 95.0%

Color and Shape: Solid, Powder

Molecular weight: 311.338

Ref: 10-F078382

Leonurine

Controlled Product

CAS: 24697-74-3

Applications Leonurine is a pseudoalkaloid that has been isolated from Leonotis leonurus. A natural product with antioxidant, anti-inflammatory and cardioprotective properties for the treatment of wild variety of conditions including stroke, cerebral thrombosis and cardiovascular diseases.
References He, C., et al.: Zhongguo Linchuang Yaolixue Yu Zhiliaoxue, 18, 1419 (2013); Nsuala, B. N., et al.: J. Ethnopharmacol., 174, 520 (2015); Sun, Y., et al.; Eur. J. Drug Metabo. Pharmacokinet., 41, 423 (2016)

Formula: C₁₄H₂₁N₃O₅

Color and Shape: Neat

Molecular weight: 311.33

Ref: TR-L329603

Leonurine

CAS: 24697-74-3

Leonurine is a polyphenolic compound that belongs to the group of natural compounds. It has been shown to have neuroprotective effects in vitro by inhibiting neuronal death at low doses. Leonurine also blocks the oxidative injury pathway, which may be related to its ability to inhibit apoptosis and reduce atherosclerotic lesion size in mice. In addition, leonurine inhibits the p-hydroxybenzoic acid (PHBA) oxidation pathway, which may contribute to its anti-inflammatory activities. Leonurine binds with high affinity and specificity to toll-like receptor 4 (TLR4), which may be related to its immunosuppressive properties.

Purity: Min. 95%

Ref: 3D-FL73876